Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.43 |
| ▸ | ITGAV | P06756 | 6/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 5/20 | 0.39 |
| ▸ | MC5R | P33032 | 5/20 | 0.39 |
| ▸ | MC3R | P41968 | 5/20 | 0.39 |
| ▸ | MC1R | Q01726 | 5/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | TSLP | Q969D9 | 1/20 | 0.35 |
| ▸ | VEGFA | P15692 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17023189 | 0.92 | ITGB3 (0.47) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL2532504 | 0.82 | ITGB3 (0.42) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL13918138 | 0.80 | ITGB3 (0.53) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL2534763 | 0.79 | ITGB3 (0.46) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL2536488 | 0.76 | ITGB3 (0.44) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL16177739 | 0.75 | ITGB3 (0.54) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL13918136 | 0.74 | ITGB3 (0.48) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL17029683 | 0.72 | ITGB3 (0.57) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL2532508 | 0.72 | ITGB3 (0.47) | ITGB3ITGAVITGB1ITGA5MC4R | |
| SCHEMBL12227486 | 0.72 | ITGB3 (0.47) | ITGB3ITGAVITGB1ITGA5MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2182974-B1 | CYCLIC AZAPEPTIDES AS INTEGRIN MARKERS | SIEMENS MEDICAL SOLUTIONS (US) | 2015-08-26 | — | — | EP | disclosed |