Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17023234 | 0.93 | KMT2A (0.48) | KMT2AMEN1LMNASMN1; SMN2NPC1 | |
| SCHEMBL17023233 | 0.90 | KMT2A (0.46) | KMT2AMEN1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL1876346 | 0.86 | KMT2A (0.47) | KMT2AMEN1LMNASMN1; SMN2NPC1 | |
| SCHEMBL1871855 | 0.84 | KMT2A (0.48) | KMT2AMEN1LMNASMN1; SMN2NPC1 | |
| SCHEMBL1875570 | 0.84 | KMT2A (0.48) | KMT2AMEN1LMNASMN1; SMN2NPC1 | |
| SCHEMBL21225109 | 0.83 | KMT2A (0.47) | KMT2AMEN1LMNASMN1; SMN2NPC1 | |
| SCHEMBL21225118 | 0.83 | KMT2A (0.47) | KMT2AMEN1LMNASMN1; SMN2NPC1 | |
| SCHEMBL21224988 | 0.83 | KMT2A (0.47) | KMT2AMEN1LMNASMN1; SMN2NPC1 | |
| SCHEMBL17023221 | 0.83 | L3MBTL1 (0.47) | KMT2AMEN1LMNASMN1; SMN2NPC1 | |
| SCHEMBL1876938 | 0.82 | KMT2A (0.48) | KMT2AMEN1LMNASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059503-B1 | AMINOPYRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES CONTAINING THE SAME | KOREA RES INST CHEM TECH (KR) | 2015-08-26 | — | — | EP | claimed |