Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17023229 | 0.94 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1SMN1; SMN2RAB9ATP53 | |
| SCHEMBL17023227 | 0.93 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1SMN1; SMN2TP53TSHR | |
| SCHEMBL17023233 | 0.93 | KMT2A (0.46) | L3MBTL1ALDH1A1SMN1; SMN2USP2GAA | |
| SCHEMBL17023232 | 0.91 | NPC1 (0.47) | L3MBTL1ALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL17023212 | 0.90 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2RAB9ATP53NPC1 | |
| SCHEMBL17023210 | 0.90 | USP2 (0.41) | L3MBTL1ALDH1A1SMN1; SMN2RAB9ATSHR | |
| SCHEMBL17023231 | 0.89 | LMNA (0.46) | ALDH1A1SMN1; SMN2RAB9ATP53NPC1 | |
| SCHEMBL17023217 | 0.89 | LMNA (0.52) | ALDH1A1SMN1; SMN2RAB9ATP53NPC1 | |
| SCHEMBL17023215 | 0.86 | KDM4E (0.49) | ALDH1A1SMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL17023234 | 0.84 | KMT2A (0.48) | L3MBTL1ALDH1A1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059503-B1 | AMINOPYRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES CONTAINING THE SAME | KOREA RES INST CHEM TECH (KR) | 2015-08-26 | — | — | EP | claimed |