Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12588776 | 0.78 | ALDH1A1 (0.37) | MEN1ALDH1A1KMT2ASMN1; SMN2BAZ2B | |
| SCHEMBL24702524 | 0.73 | — | — | |
| SCHEMBL7323969 | 0.70 | ALDH1A1 (0.44) | ALDH1A1POLBTDP1MAPT | |
| Butanedione SCHEMBL5077409 | 0.69 | TSHR (0.44) | SMN1; SMN2BAZ2BTP53MAPT | |
| SCHEMBL2927288 | 0.67 | MEN1 (0.34) | MEN1ALDH1A1KMT2A | |
| SCHEMBL6793523 | 0.67 | ALDH1A1 (0.33) | MEN1ALDH1A1KMT2ABAZ2BPOLB | |
| SCHEMBL13696907 | 0.67 | HTT (0.37) | MEN1ALDH1A1KMT2A | |
| SCHEMBL15592911 | 0.66 | MEN1 (0.36) | MEN1ALDH1A1KMT2ASMN1; SMN2BAZ2B | |
| SCHEMBL289021 | 0.65 | — | — | |
| SCHEMBL8114600 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627634-B1 | A NEW DIMEDON DERIVATIVE AND A METHOD FOR THE PURIFICATION OF PNA AND PEPTIDE OLIGOMERS | DEUTSCHES KREBSFORSCH (DE) | 2015-08-26 | — | — | EP | disclosed |