SCHEMBL7323969

SCHEMBL7323969

CC(N)=C1C(=O)CC(C)(C)CC1=O

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.44
MAPT P10636 5/20 0.43
KDM4E B2RXH2 3/20 0.43
POLB P06746 2/20 0.42
MAOA P21397 1/20 0.40
GAA P10253 2/20 0.39
HTT P42858 3/20 0.39
LMNA P02545 1/20 0.39
ATM Q13315 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37
GLA P06280 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TDP2 O95551 1/20 0.35
SMAD3 P84022 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KDM4C Q9H3R0 1/20 0.35
NCOA1 Q15788 1/20 0.35
NCOA3 Q9Y6Q9 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8083467 0.80 ALDH1A1 (0.47) ALDH1A1MAPTKDM4EPOLBMAOA
SCHEMBL13191817 0.78 ALDH1A1 (0.45) ALDH1A1MAPTKDM4EPOLBMAOA
SCHEMBL7323961 0.76 ALDH1A1 (0.48) ALDH1A1MAPTKDM4EPOLBMAOA
SCHEMBL25139402 0.76 ALDH1A1 (0.40) ALDH1A1MAPTKDM4EPOLBMAOA
SCHEMBL21786201 0.73 ALDH1A1 (0.46) ALDH1A1MAPTKDM4EPOLBMAOA
SCHEMBL13840142 0.73 ALDH1A1 (0.44) ALDH1A1MAPTKDM4EPOLBMAOA
SCHEMBL12870972 0.73 ALDH1A1 (0.41) ALDH1A1MAPTKDM4EPOLBMAOA
SCHEMBL2324941 0.73
SCHEMBL14959874 0.71 POLB (0.46) ALDH1A1MAPTKDM4EPOLBMAOA
SCHEMBL17336270 0.71 PTGES (0.39) ALDH1A1MAPTKDM4EPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10280194-B2 Short chain PEGylation of amino acid monomers glutamine, lysine and peptides formed thereby CLEMSON UNIVERSITY (US) 2019-05-07 US claimed
US-20170137460-A1 Short Chain PEGylation of Amino Acid Monomers Glutamine, Lysine and Peptides Formed Thereby CLEMSON UNIVERSITY 2017-05-18 US claimed
EP-3151828-A1 SHORT CHAIN PEGYLATION OF AMINO ACID MONOMERS GLUTAMINE AND LYSINE AND PEPTIDES FORMED THEREBY Clemson University (US) 2017-04-12 EP claimed
WO-2015191433-A1 SHORT CHAIN PEGYLATION OF AMINO ACID MONOMERS GLUTAMINE AND LYSINE AND PEPTIDES FORMED THEREBY CLEMSON UNIVERSITY (US) 2015-12-17 WO claimed
EP-1119529-B1 CHEMICAL CONSTRUCTS GLAXO GROUP LTD (GB) 2003-09-17 EP claimed
US-20250375544-A1 DUAL MODE RADIOTRACER AND -THERAPEUTICS UNIV MUENCHEN TECH (DE) 2025-12-11 US disclosed
EP-3844143-B1 TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION GYROS PROTEIN TECH AB (SE) 2024-01-17 EP disclosed
EP-4010352-B1 A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES GYROS PROTEIN TECH AB (SE) 2023-10-18 EP disclosed
EP-4219446-A2 TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION Gyros Protein Technologies AB (SE) 2023-08-02 EP disclosed
EP-4023250-A1 DUAL MODE RADIOTRACER AND -THERAPEUTICS Technische Universität München (DE) 2022-07-06 EP disclosed
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2022-05-10 US disclosed
WO-2020043747-A1 TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION Belyntic GmbH (DE) 2020-03-05 WO disclosed
US-10280194-B2 Short chain PEGylation of amino acid monomers glutamine, lysine and peptides formed thereby CLEMSON UNIVERSITY (US) 2019-05-07 US disclosed
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2017-11-02 US disclosed
US-20170137460-A1 Short Chain PEGylation of Amino Acid Monomers Glutamine, Lysine and Peptides Formed Thereby CLEMSON UNIVERSITY 2017-05-18 US disclosed
EP-3151828-A1 SHORT CHAIN PEGYLATION OF AMINO ACID MONOMERS GLUTAMINE AND LYSINE AND PEPTIDES FORMED THEREBY Clemson University (US) 2017-04-12 EP disclosed
WO-2015191433-A1 SHORT CHAIN PEGYLATION OF AMINO ACID MONOMERS GLUTAMINE AND LYSINE AND PEPTIDES FORMED THEREBY CLEMSON UNIVERSITY (US) 2015-12-17 WO disclosed
EP-1119529-B1 CHEMICAL CONSTRUCTS GLAXO GROUP LTD (GB) 2003-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10280194-B2 Short chain PEGylation of amino acid monomers glutamine, lysine and peptides formed thereby GLUL, ASNS, ARGLU1 ALDH1A1 4119/4885MAPT 1659/4885KDM4E 1374/4885
US-20170137460-A1 Short Chain PEGylation of Amino Acid Monomers Glutamine, Lysine and Peptides Formed Thereby GLUL, ASNS, ARGLU1 ALDH1A1 4119/4885MAPT 1659/4885KDM4E 1374/4885
US-20250375544-A1 DUAL MODE RADIOTRACER AND -THERAPEUTICS MAN2B1, GBA1, SSTR1 ALDH1A1 625/4885MAPT 3475/4885KDM4E 2486/4885
US-11324827-B2 Multifunctionalized polyethylene glycol derivative and preparation method therefor HDGF, F11, F12 ALDH1A1 1582/4885MAPT 4184/4885KDM4E 4115/4885
US-20170312363-A1 MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR HDGF, F11, F12 ALDH1A1 1582/4885MAPT 4184/4885KDM4E 4115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.