Phthalimide

Phthalimide

SCHEMBL1702379

O=C1NC(=O)c2ccccc21.c1ccncc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GSK3B P49841 2/20 0.68
▸ CASP3 P42574 2/20 0.58
▸ CASP7 P55210 2/20 0.58
▸ CASP6 P55212 2/20 0.58
▸ CASP8 Q14790 2/20 0.58
▸ CASP2 P42575 1/20 0.58
▸ SMN1; SMN2 Q16637 4/20 0.47
▸ LMNA P02545 3/20 0.47
▸ MAPK1 P28482 3/20 0.47
▸ HSD17B10 Q99714 2/20 0.47
▸ KDM4E B2RXH2 2/20 0.46
▸ ALDH1A1 P00352 2/20 0.46
▸ PARP1 P09874 2/20 0.45
▸ PDGFRA P16234 1/20 0.45
▸ FER P16591 1/20 0.45
▸ LTK P29376 1/20 0.45
▸ CDK8 P49336 1/20 0.45
▸ ACVR1 Q04771 1/20 0.45
▸ LRRK2 Q5S007 1/20 0.45
▸ DYRK1B Q9Y463 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalimide SCHEMBL7784689 0.98 GSK3B (0.65) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL7784687 0.98 GSK3B (0.65) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL27524014 0.90 GSK3B (0.56) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL8603353 0.89 GSK3B (0.54) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL3984602 0.85 GSK3B (0.94) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL6890310 0.83 GSK3B (0.88) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL28619195 0.83 GSK3B (0.88) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL29664386 0.83 GSK3B (0.88) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL6244849 0.83 GSK3B (0.88) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL29366030 0.83 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146192-A Phthalimide quaternary ammonium salt compound and application thereof 华东理工大学 2024-06-07 — — CN disclosed
CN-118146192-A Phthalimide quaternary ammonium salt compound and application thereof 华东理工大学 2024-06-07 — — CN disclosed
CN-107033145-B Benzothiazine and benzothiadiazines compound and preparation and application 浙江大学 2019-11-22 — — CN disclosed
US-9777213-B2 Phosphor, phosphor-containing composition and light-emitting unit using phosphor, and image display device and lighting device using light-emitting unit MITSUBISHI CHEMICAL CORPORATION (JP) 2017-10-03 — — US disclosed
CN-107033145-A Benzothiazine and benzothiadiazines compound and preparation and application 浙江大学 2017-08-11 — — CN disclosed
US-20150291879-A1 PHOSPHOR, PHOSPHOR-CONTAINING COMPOSITION AND LIGHT-EMITTING UNIT USING PHOSPHOR, AND IMAGE DISPLAY DEVICE AND LIGHTING DEVICE USING LIGHT-EMITTING UNIT MITSUBISHI CHEMICAL CORPORATION (JP) 2015-10-15 — — US disclosed
EP-2588487-A1 A NEW METHOD OF USING N-THIO COMPOUNDS FOR OLIGONUCLEOTIDE SYNTHESIS Girindus America, Inc. (US) 2013-05-08 — — EP disclosed
WO-2012001126-A1 A NEW METHOD OF USING N-THIO COMPOUNDS FOR OLIGONUCLEOTIDE SYNTHESIS GIRINDUS AMERICA, INC. (US) 2012-01-05 — — WO disclosed
CN-1175512-C Non-aqueous electrolyte and non-aqueous electrolyte cell ���µ�����ҵ��ʽ���� 2004-11-10 — — CN disclosed
CN-1174515-C Non-aqueous electrolyte cell ���µ�����ҵ��ʽ���� 2004-11-03 — — CN disclosed
CN-1338129-A Non-aqueous electrolyte cell MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2002-02-27 — — CN disclosed
CN-1338128-A Non-aqueous electrolyte and non-aqueous electrolyte cell MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2002-02-27 — — CN disclosed
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