Phthalimide

Phthalimide

SCHEMBL3984602

O=C1NC(=O)c2ccccc21.c1ccccc1

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.94
CASP3 P42574 2/20 0.75
CASP7 P55210 2/20 0.75
CASP6 P55212 2/20 0.75
CASP8 Q14790 2/20 0.75
CASP2 P42575 1/20 0.75
LMNA P02545 3/20 0.58
MAPK1 P28482 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
HSD17B10 Q99714 1/20 0.58
PARP1 P09874 2/20 0.56
PDGFRA P16234 1/20 0.56
FER P16591 1/20 0.56
LTK P29376 1/20 0.56
CDK8 P49336 1/20 0.56
ACVR1 Q04771 1/20 0.56
LRRK2 Q5S007 1/20 0.56
DYRK1B Q9Y463 1/20 0.56
MAOA P21397 6/20 0.54
MAOB P27338 6/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalimide SCHEMBL10192661 0.97 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL7771670 0.97 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL30125197 0.97 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL11040503 0.97 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL64 0.97 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL29366030 0.97 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL1205294 0.94 GSK3B (0.94) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL5742518 0.94 GSK3B (0.94) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL9421750 0.94 GSK3B (0.94) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL228977 0.94 GSK3B (0.94) GSK3BCASP3CASP7CASP6CASP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103119178-B Method and device for detecting nucleic acid, and kit 株式会社钟化 2017-05-17 CN disclosed
CN-103403190-B Method for detecting nucleic acid, and device and kit for use in the method 株式会社钟化 2017-04-12 CN disclosed
CN-102355823-A Composition comprising suspended pesticide, salt and polysaccharide BASF SE 2012-02-15 CN disclosed
CN-1867331-B Thalidomide analogs as TNF-alpha modulators US GOV HEALTH & HUMAN SERV (US) 2010-05-26 CN disclosed
WO-2009056782-A1 LUMINESCENCE UCL BUSINESS PLC (GB) 2009-05-07 WO disclosed
CN-1867331-A Thalidomide analogs as TNF-alpha modulators US GOV HEALTH & HUMAN SERV (US) 2006-11-22 CN disclosed