Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.65 |
| ▸ | CASP3 | P42574 | 2/20 | 0.56 |
| ▸ | CASP7 | P55210 | 2/20 | 0.56 |
| ▸ | CASP6 | P55212 | 2/20 | 0.56 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.56 |
| ▸ | CASP2 | P42575 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | FER | P16591 | 1/20 | 0.43 |
| ▸ | LTK | P29376 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalimide SCHEMBL1702379 | 0.98 | GSK3B (0.68) | GSK3BCASP3CASP7CASP6CASP8 | |
| Phthalimide SCHEMBL7784689 | 0.96 | GSK3B (0.65) | GSK3BCASP3CASP7CASP6CASP8 | |
| Phthalimide SCHEMBL27524014 | 0.88 | GSK3B (0.56) | GSK3BCASP3CASP7CASP6CASP8 | |
| Phthalimide SCHEMBL8603353 | 0.87 | GSK3B (0.54) | GSK3BCASP3CASP7CASP6CASP8 | |
| Phthalimide SCHEMBL3984602 | 0.83 | GSK3B (0.94) | GSK3BCASP3CASP7CASP6CASP8 | |
| Phthalimide SCHEMBL1205291 | 0.83 | GSK3B (0.94) | GSK3BCASP3CASP7CASP6CASP8 | |
| Phthalimide SCHEMBL9229 | 0.83 | GSK3B (0.94) | GSK3BCASP3CASP7CASP6CASP8 | |
| Phthalimide SCHEMBL29664386 | 0.81 | GSK3B (0.88) | GSK3BCASP3CASP7CASP6CASP8 | |
| Phthalimide SCHEMBL6890310 | 0.81 | GSK3B (0.88) | GSK3BCASP3CASP7CASP6CASP8 | |
| Phthalimide SCHEMBL28619195 | 0.81 | GSK3B (0.88) | GSK3BCASP3CASP7CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140805-A1 | AMIDO POLYBIGUANIDES AND THE USE THEREOF AS ANTIMICROBIAL AGENTS | Alcon Laboratories, Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| EP-1140804-A1 | BIS-AMIDO POLYBIGUANIDES AND THE USE THEREOF TO DISINFECT CONTACT LENSES AND PRESERVE PHARMACEUTICAL COMPOSITIONS | Alcon Laboratories, Inc. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035861-A1 | BIS-AMIDO POLYBIGUANIDES AND THE USE THEREOF TO DISINFECT CONTACT LENSES AND PRESERVE PHARMACEUTICAL COMPOSITIONS | ALCON LABORATORIES, INC. (US) | 2000-06-22 | — | — | WO | disclosed |
| WO-2000035862-A1 | AMIDO POLYBIGUANIDES AND THE USE THEREOF AS ANTIMICROBIAL AGENTS | ALCON LABORATORIES, INC. (US) | 2000-06-22 | — | — | WO | disclosed |