Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | CDC25C | P30307 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3152114 | 0.83 | ALDH1A1 (0.39) | CYP3A4ALDH1A1CYP2C9RECQLTDP1 | |
| SCHEMBL29167123 | 0.81 | ALDH1A1 (0.38) | CYP3A4ALDH1A1CYP2C9TDP1ACHE | |
| SCHEMBL30785057 | 0.81 | ALDH1A1 (0.38) | CYP3A4ALDH1A1CYP2C9TDP1ACHE | |
| SCHEMBL22109656 | 0.80 | ALDH1A1 (0.41) | CYP3A4ALDH1A1CYP2C9RECQLTDP1 | |
| SCHEMBL30785053 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRMAPTKDM4E | |
| SCHEMBL28903605 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRMAPTKDM4E | |
| SCHEMBL19825375 | 0.79 | RECQL (0.43) | CYP3A4ALDH1A1CYP2C9RECQLTDP1 | |
| SCHEMBL19404067 | 0.79 | RECQL (0.43) | CYP3A4ALDH1A1CYP2C9RECQLTDP1 | |
| SCHEMBL21496386 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TDP1TSHRMAPTKDM4E | |
| SCHEMBL30018842 | 0.78 | ALDH1A1 (0.36) | ALDH1A1TDP1TSHRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114460203-B | Method for simultaneously detecting methyl p-toluenesulfonate, ethyl p-toluenesulfonate and isopropyl p-toluenesulfonate in medicine | 浙江海正药业股份有限公司 | 2023-12-22 | — | — | CN | claimed |
| CN-114460203-A | Method for simultaneously detecting methyl p-toluenesulfinate, ethyl p-toluenesulfinate and isopropyl p-toluenesulfinate in medicine | 浙江海正药业股份有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-114460203-B | Method for simultaneously detecting methyl p-toluenesulfonate, ethyl p-toluenesulfonate and isopropyl p-toluenesulfonate in medicine | 浙江海正药业股份有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-114460203-B | Method for simultaneously detecting methyl p-toluenesulfonate, ethyl p-toluenesulfonate and isopropyl p-toluenesulfonate in medicine | 浙江海正药业股份有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-115286542-B | Preparation method of sulfinate compound | 浙江工业大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-115286542-A | Preparation method of sulfinate compound | 浙江工业大学 | 2022-11-04 | — | — | CN | disclosed |
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |
| CN-114460203-A | Method for simultaneously detecting methyl p-toluenesulfinate, ethyl p-toluenesulfinate and isopropyl p-toluenesulfinate in medicine | 浙江海正药业股份有限公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-114460203-A | Method for simultaneously detecting methyl p-toluenesulfinate, ethyl p-toluenesulfinate and isopropyl p-toluenesulfinate in medicine | 浙江海正药业股份有限公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-114460203-A | Method for simultaneously detecting methyl p-toluenesulfinate, ethyl p-toluenesulfinate and isopropyl p-toluenesulfinate in medicine | 浙江海正药业股份有限公司 | 2022-05-10 | — | — | CN | disclosed |
| WO-2021226009-A1 | SYNTHESIS OF VINYL CYCLOBUTYL INTERMEDIATES | AMGEN INC. (US) | 2021-11-11 | — | — | WO | disclosed |
| WO-2021225823-A1 | SYNTHESIS OF VINYLIC PROTECTED ALCOHOL INTERMEDIATES | AMGEN INC. (US) | 2021-11-11 | — | — | WO | disclosed |
| WO-2021178818-A2 | THERAPEUTIC AGENTS AND CONJUGATES THEREOF | BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) | 2021-09-10 | — | — | WO | disclosed |
| US-9908846-B2 | Composition, synthesis, and use of new arylsulfonyl isonitriles | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2018-03-06 | — | — | US | disclosed |
| US-9908846-B2 | Composition, synthesis, and use of new arylsulfonyl isonitriles | DUQUESNE UNIVERSITY OF THE HOLY SPIRIT (US) | 2018-03-06 | — | — | US | disclosed |
| EP-3219503-A1 | PROCESS FOR MANUFACTURING A LASER MARKABLE PACKAGING | AGFA-GEVAERT (BE) | 2017-09-20 | — | — | EP | disclosed |
| WO-2016050210-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | 厦门赛诺邦格生物科技有限公司 | 2016-04-07 | — | — | WO | disclosed |
| US-20150239833-A1 | COMPOSITION, SYNTHESIS, AND USE OF NEW ARYLSULFONYL ISONITRILES | DUQUESNE UNIVERSITY OF THE HOLY GHOST (US) | 2015-08-27 | — | — | US | disclosed |
| US-20150239833-A1 | COMPOSITION, SYNTHESIS, AND USE OF NEW ARYLSULFONYL ISONITRILES | DUQUESNE UNIVERSITY OF THE HOLY GHOST (US) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239833-A1 | COMPOSITION, SYNTHESIS, AND USE OF NEW ARYLSULFONYL ISONITRILES | SRMS, AADAC, CYP3A4 | CYP3A4 3/4885ALDH1A1 1240/4885CYP2C9 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.