Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | MDH1 | P40925 | 8/20 | 0.43 |
| ▸ | MDH2 | P40926 | 8/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | APAF1 | O14727 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17024094 | 0.86 | NPC1 (0.45) | HIF1AHTTARMAPTTDP1 | |
| SCHEMBL17024101 | 0.84 | MAPT (0.50) | SMN1; SMN2HIF1AHTTARMEN1 | |
| SCHEMBL7879426 | 0.83 | CYP3A4 (0.61) | CYP3A4SMN1; SMN2SHBGMDH1MDH2 | |
| SCHEMBL15677164 | 0.80 | AR (0.62) | CYP3A4SMN1; SMN2SHBGMDH1MDH2 | |
| SCHEMBL17024104 | 0.79 | KMT2A (0.55) | SMN1; SMN2HIF1AHTTARMEN1 | |
| SCHEMBL2108184 | 0.77 | CYP3A4 (0.62) | CYP3A4SMN1; SMN2SHBGMDH1MDH2 | |
| SCHEMBL2108647 | 0.77 | SMN1; SMN2 (0.54) | CYP3A4SMN1; SMN2SHBGMDH1MDH2 | |
| SCHEMBL15677151 | 0.77 | SMN1; SMN2 (0.54) | CYP3A4SMN1; SMN2SHBGMDH1MDH2 | |
| SCHEMBL10612296 | 0.77 | CYP3A4 (0.54) | CYP3A4SMN1; SMN2SHBGMDH1MDH2 | |
| SCHEMBL10412598 | 0.75 | SMN1; SMN2 (0.60) | CYP3A4SMN1; SMN2SHBGMDH1MDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150238401-A1 | PROPYL-PHENYL-ETHER DERIVATIVE, AND MELANOGENESIS INHIBITOR, SKIN-LIGHTENING AGENT, ANTIMICROBIAL AGENT AND COSMETIC CONTAINING SAID PROPYL-PHENYL-ETHER DERIVATIVE | SEIWA KASEI COMPANY, LIMITED (JP) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150238401-A1 | PROPYL-PHENYL-ETHER DERIVATIVE, AND MELANOGENESIS INHIBITOR, SKIN-LIGHTENING AGENT, ANTIMICROBIAL AGENT AND COSMETIC CONTAINING SAID PROPYL-PHENYL-ETHER DERIVATIVE | TYR, MITF, MC1R | CYP3A4 815/4885SMN1; SMN2 4407/4885SHBG 2000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.