Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MDH1 | P40925 | 2/20 | 0.41 |
| ▸ | MDH2 | P40926 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15677164 | 0.85 | AR (0.62) | SMN1; SMN2CYP3A4ARHTTHIF1A | |
| SCHEMBL2108029 | 0.81 | CYP3A4 (0.84) | SMN1; SMN2CYP3A4HTTHIF1ASHBG | |
| SCHEMBL9636026 | 0.80 | ALDH1A1 (0.57) | SMN1; SMN2CYP3A4ARHTTHIF1A | |
| SCHEMBL28000802 | 0.79 | CYP3A4 (0.61) | SMN1; SMN2CYP3A4ARHTTHIF1A | |
| SCHEMBL28001129 | 0.79 | CYP3A4 (0.61) | SMN1; SMN2CYP3A4ARHTTHIF1A | |
| SCHEMBL7879426 | 0.79 | CYP3A4 (0.61) | SMN1; SMN2CYP3A4ARHTTHIF1A | |
| SCHEMBL1592415 | 0.79 | CYP3A4 (0.81) | SMN1; SMN2CYP3A4HTTHIF1ASHBG | |
| SCHEMBL15677151 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP3A4ARHTTHIF1A | |
| SCHEMBL2108647 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2CYP3A4ARHTTHIF1A | |
| SCHEMBL2108184 | 0.77 | CYP3A4 (0.62) | SMN1; SMN2CYP3A4ARHTTHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4892671-A | FUEL AND OIL ADDITIVES | CIBA-GEIGY CORPORATION (US) | 1990-01-09 | — | — | US | disclosed |