Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PTPRA | P18433 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5109203 | 0.74 | POLB (0.42) | POLBOPRM1ALDH1A1TSHRGAA | |
| SCHEMBL5109201 | 0.74 | POLB (0.42) | POLBOPRM1ALDH1A1TSHRGAA | |
| SCHEMBL28679009 | 0.74 | POLB (0.44) | POLBOPRM1ALDH1A1TSHRGAA | |
| SCHEMBL4953717 | 0.74 | POLB (0.44) | POLBOPRM1ALDH1A1TSHRGAA | |
| SCHEMBL4953723 | 0.74 | POLB (0.44) | POLBOPRM1ALDH1A1TSHRGAA | |
| SCHEMBL2475256 | 0.73 | CTSK (0.39) | POLBTSHRPPARGPPARAPTPRA | |
| SCHEMBL2475253 | 0.73 | CTSK (0.39) | POLBTSHRPPARGPPARAPTPRA | |
| SCHEMBL7018249 | 0.72 | ALDH1A1 (0.43) | POLBOPRM1ALDH1A1KDM4ETSHR | |
| SCHEMBL7018248 | 0.72 | ALDH1A1 (0.43) | POLBOPRM1ALDH1A1KDM4ETSHR | |
| SCHEMBL4302480 | 0.72 | POLB (0.43) | POLBOPRM1ALDH1A1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160220647-A1 | PROTEINS FOR TARGETING NEURONAL NITRIC OXIDE SYNTHASE TO MUSCLE SARCOLEMMA AND RELATED METHODS OF USE | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2016-08-04 | — | — | US | disclosed |
| US-9243037-B2 | Gramicidin a mutants that function as antibiotics with improved solubility and reduced toxicity | TRUSTEES OF BOSTON COLLEGE (US) | 2016-01-26 | — | — | US | disclosed |
| US-20150239936-A1 | GRAMICIDIN A MUTANTS THAT FUNCTION AS ANTIBIOTICS WITH IMPROVED SOLUBILITY AND REDUCED TOXICITY | TRUSTEES OF BOSTON COLLEGE | 2015-08-27 | — | — | US | disclosed |