Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 8/20 | 0.61 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17025347 | 1.00 | PDE2A (0.61) | PDE2ALIPGTAS2R14SCN10AKDM4E | |
| SCHEMBL18075239 | 0.86 | PDE2A (0.68) | PDE2ALIPGSCN10AKIF11HTR2A | |
| SCHEMBL30481795 | 0.86 | PDE2A (0.68) | PDE2ALIPGSCN10AKIF11HTR2A | |
| SCHEMBL12306470 | 0.84 | PDE2A (0.46) | PDE2ATAS2R14ALDH1A1KIF11HTR2A | |
| SCHEMBL8750547 | 0.82 | ALDH1A1 (0.42) | PDE2ASCN10AKDM4EALDH1A1HPGD | |
| SCHEMBL23675536 | 0.81 | PDE2A (0.61) | PDE2ALIPGSCN10AHTR2AHTR2C | |
| SCHEMBL19696153 | 0.81 | PDE2A (0.61) | PDE2ALIPGSCN10AHTR2AHTR2C | |
| SCHEMBL10107301 | 0.81 | PDE2A (0.61) | PDE2ALIPGSCN10AHTR2AHTR2C | |
| SCHEMBL22717043 | 0.81 | PDE2A (0.61) | PDE2ALIPGSCN10AHTR2AHTR2C | |
| SCHEMBL27624246 | 0.80 | PDE2A (0.44) | PDE2ATAS2R14KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150239889-A1 | PYRAZOLOPYRIMIDINE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239889-A1 | PYRAZOLOPYRIMIDINE COMPOUND | HIF1AN, EGLN2, EGLN3 | PDE2A 2288/4885LIPG 4485/4885TAS2R14 2233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.