SCHEMBL1702579

SCHEMBL1702579

CCOC(=O)C([C]=O)CC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
LMNA P02545 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ALOX15 P16050 1/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SOAT1 P35610 1/20 0.39
CAD P27708 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TRPA1 O75762 1/20 0.36
TSHR P16473 2/20 0.35
KMT2A Q03164 2/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
POLB P06746 1/20 0.34
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9771153 0.82 ALDH1A1 (0.39) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL11326519 0.82 ALDH1A1 (0.39) ALDH1A1LMNATSHRPOLBCA1
SCHEMBL893423 0.81
SCHEMBL4734875 0.80 ALDH1A1 (0.32) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL10920266 0.79 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL10600518 0.76 ZDHHC7 (0.44) LMNACA2
SCHEMBL9091558 0.75 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10ALOX15MGAM
SCHEMBL1191194 0.73
SCHEMBL891222 0.72
SCHEMBL20551243 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1001943-B1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM AVENTIS PHARMA SA (FR) 2003-12-17 EP claimed
US-6380197-B1 FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES AVENTIS PHARMA S. A. (FR) 2002-04-30 US claimed
EP-1001943-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM Aventis Pharma S.A. (FR) 2000-05-24 EP claimed
WO-1999003843-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM RHONE-POULENC RORER S.A. (FR) 1999-01-28 WO claimed
EP-2440524-A1 STERICALLY HINDERED AMINE STABILIZERS BASF SE (DE) 2012-04-18 EP disclosed
WO-2010142572-A1 STERICALLY HINDERED AMINE STABILIZERS BASF SE (DE) 2010-12-16 WO disclosed
WO-2008059014-A2 ANTITUBERCULOSIS AGENTS WITH ALKYLIDENE OR ALKYL SIDE CHAIN UNIVERSIDAD DE SALAMANCA (ES) 2008-05-22 WO disclosed
EP-1001943-B1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM AVENTIS PHARMA SA (FR) 2003-12-17 EP disclosed
US-6380197-B1 FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES AVENTIS PHARMA S. A. (FR) 2002-04-30 US disclosed
EP-1001943-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM Aventis Pharma S.A. (FR) 2000-05-24 EP disclosed
WO-1999003843-A1 POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM RHONE-POULENC RORER S.A. (FR) 1999-01-28 WO disclosed
US-5008290-A Anticoagulant DR. KARL THOMAE GMBH (DE) 1991-04-16 US disclosed
US-4749691-A Peptide, process for preparation thereof and use thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1988-06-07 US disclosed
US-4725582-A IMMUNE RESPONSE ENHANCERS FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1988-02-16 US disclosed
EP-0025842-B1 PEPTIDES, PROCESS FOR THEIR PREPARATION, THEIR PHARMACEUTICAL COMPOSITIONS AND THEIR INTERMEDIATES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1987-06-03 EP disclosed
US-4539155-A New peptide, process for preparation thereof and use thereof FUISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1985-09-03 US disclosed
US-4504584-A PEPTIDE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-03-12 US disclosed
US-4458078-A SYNTHESIS OF OLIGOPEPTIDES FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1984-07-03 US disclosed
US-4311640-A ANTIBIOTIC FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1982-01-19 US disclosed
EP-0025842-A2 Peptides, process for their preparation, their pharmaceutical compositions and their intermediates FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-04-01 EP disclosed