Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20261949 | 0.82 | ALDH1A1 (0.34) | ALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL1702579 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL893423 | 0.76 | — | — | |
| SCHEMBL10483850 | 0.73 | CA2 (0.39) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL11326519 | 0.72 | ALDH1A1 (0.39) | ALDH1A1LMNA | |
| SCHEMBL332266 | 0.71 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL17710662 | 0.70 | — | — | |
| SCHEMBL27769372 | 0.68 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL1485969 | 0.68 | ALDH1A1 (0.33) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL891222 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059014-A2 | ANTITUBERCULOSIS AGENTS WITH ALKYLIDENE OR ALKYL SIDE CHAIN | UNIVERSIDAD DE SALAMANCA (ES) | 2008-05-22 | — | — | WO | claimed |