SCHEMBL1702641

SCHEMBL1702641

CCCN(CCC)c1ccc(C=NN(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.48
GAA P10253 6/20 0.48
MAPK1 P28482 3/20 0.48
HTT P42858 1/20 0.48
KMT2A Q03164 5/20 0.46
MEN1 O00255 4/20 0.46
ALDH1A1 P00352 10/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MCL1 Q07820 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
G6PC1 P35575 1/20 0.43
KDM4E B2RXH2 7/20 0.42
ESRRG P62508 1/20 0.41
USP2 O75604 1/20 0.41
TDP1 Q9NUW8 3/20 0.40
LMNA P02545 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1702640 1.00 MAPT (0.48) MAPTGAAMAPK1HTTKMT2A
SCHEMBL1703027 0.91 GAA (0.46) MAPTGAAMAPK1HTTKMT2A
SCHEMBL1703028 0.91 GAA (0.46) MAPTGAAMAPK1HTTKMT2A
SCHEMBL122069 0.87 MAPT (0.61) MAPTGAAMAPK1HTTKMT2A
SCHEMBL122070 0.87 MAPT (0.61) MAPTGAAMAPK1HTTKMT2A
SCHEMBL16745300 0.85 APP (0.38) MAPTGAAMAPK1HTTKMT2A
SCHEMBL332093 0.81 CYP1A2 (0.53) MAPTGAAMAPK1HTTKMT2A
SCHEMBL332094 0.81 CYP1A2 (0.53) MAPTGAAMAPK1HTTKMT2A
SCHEMBL7821078 0.81 MAPT (0.50) MAPTGAAMAPK1HTTKMT2A
SCHEMBL7821079 0.81 MAPT (0.50) MAPTGAAMAPK1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6645686-B1 Electrophotographic imaging members XEROX CORPORATION 2003-11-11 US claimed
EP-0001599-B1 ELECTROPHOTOGRAPHIC RECORDING MATERIAL AND ITS APPLICATION IN A COPYING PROCESS International Business Machines Corporation (US) 1981-10-21 EP claimed
US-4150987-A ELECTROGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1979-04-24 US claimed
US-20150185627-A1 Method of Producing Photoconductors Having Titanyl Phthalocyanine and Bisazo Pigments in Dual Charge Generation Layers LEXMARK INTERNATIONAL, INC. (US) 2015-07-02 US disclosed
US-20150185629-A1 Photoconductors Having Titanyl Phthalocyanine and Bisazo Pigments in Dual Charge Generation Layers LEXMARK INTERNATIONAL, INC. (US) 2015-07-02 US disclosed
US-8178265-B2 Electrophotographic photoreceptor having a spectral marker and electrophotographic printer using the same LEXMARK INTERNATIONAL, INC. (US) 2012-05-15 US disclosed
EP-1089130-B1 Process for fabricating an electrophotographic imaging member XEROX CORP (US) 2012-04-18 EP disclosed
US-7955769-B2 Control of crazing, cracking or crystallization of a charge transport layer in a photoconductor LEXMARK INTERNATIONAL, INC. (US) 2011-06-07 US disclosed
US-20100167191-A1 Electrophotographic Photoreceptor Having a Spectral Marker and Electrophotographic Printer Using the Same BANK TRUST COMPANY, NATIONAL ASSOCIATION 2010-07-01 US disclosed
US-20090233196-A1 Photoconductors Containing Copper Phthalocyanine and Titanyl Phthalocyanine in the Charge Generation Layer LEXMARK INTERNATIONAL, INC. 2009-09-17 US disclosed
US-20090202928-A1 Control of Crazing, Cracking or Crystallization of a Charge Transport Layer in a Photoconductor BANK TRUST COMPANY, NATIONAL ASSOCIATION 2009-08-13 US disclosed
US-4959287-A Xeroradiographic imaging member XEROX CORPORATION (US) 1990-09-25 US disclosed
US-4933244-A Phenolic epoxy polymer or polyester and charge transporting small molecule at interface between a charge generator layer and a charge transport layer XEROX CORPORATION (US) 1990-06-12 US disclosed
US-4921773-A Process for preparing an electrophotographic imaging member XEROX CORPORATION (US) 1990-05-01 US disclosed
US-4895783-A SOLVENT RESISTANCE, WEAR RESISTANCE XEROX CORPORATION (US) 1990-01-23 US disclosed
US-4515882-A CHARGE TRANSFER COMPOUNDS AND CHARGE INJECTION ENABLING PARTICLES XEROX CORPORATION (US) 1985-05-07 US disclosed
US-4399206-A Disazo electrophotographic photosensitive member CANON KABUSHIKI KAISHA (JP) 1983-08-16 US disclosed
EP-0001599-B1 ELECTROPHOTOGRAPHIC RECORDING MATERIAL AND ITS APPLICATION IN A COPYING PROCESS International Business Machines Corporation (US) 1981-10-21 EP disclosed
EP-0001599-A1 Electrophotographic recording material and its application in a copying process International Business Machines Corporation (US) 1979-05-02 EP disclosed
US-4150987-A ELECTROGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1979-04-24 US disclosed