Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17027204 | 0.80 | IDO1 (0.45) | POLBMEN1KMT2AIDO1HTR1A | |
| SCHEMBL22158064 | 0.71 | FEN1 (0.44) | DDR1HTR6 | |
| SCHEMBL18581219 | 0.70 | IDO1 (0.45) | MEN1KMT2AIDO1HTR1ADRD2 | |
| SCHEMBL17027144 | 0.70 | MEN1 (0.46) | MEN1KMT2AIDO1HTR1ADRD2 | |
| SCHEMBL17026986 | 0.70 | MEN1 (0.43) | MEN1KMT2AIDO1HTR1ADRD2 | |
| Pyridine SCHEMBL18581078 | 0.68 | MAP2K4 (0.40) | MEN1KMT2AIDO1HTR1ADRD2 | |
| SCHEMBL17027023 | 0.67 | KIF11 (0.41) | MEN1KMT2ADDR1DRD2HTR6 | |
| SCHEMBL7128846 | 0.67 | CA1 (0.42) | NR1H3 | |
| SCHEMBL27946710 | 0.65 | KIF11 (0.47) | MEN1KMT2AIDO1HTR1ADRD2 | |
| SCHEMBL27691865 | 0.65 | MEN1 (0.53) | MEN1KMT2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107910-A1 | NEW PHENYLAZETIDINE, CARBOXYLATE OR CARBOXAMIDE COMPOUNDS | INVENTIVA (FR) | 2016-12-28 | — | — | EP | disclosed |
| WO-2015124868-A1 | NEW PHENYLAZETIDINE, CARBOXYLATE OR CARBOXAMIDE COMPOUNDS | INVENTIVA (FR) | 2015-08-27 | — | — | WO | disclosed |