Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 20/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12478767 | 0.91 | PTK2 (0.35) | PTK2 | |
| SCHEMBL12478676 | 0.88 | HPGD (0.36) | PTK2 | |
| SCHEMBL17027297 | 0.82 | RXFP1 (0.40) | PTK2FLT4 | |
| SCHEMBL17027345 | 0.78 | PTK2 (0.54) | PTK2FLT4 | |
| SCHEMBL14617540 | 0.77 | SDHB (0.39) | PTK2 | |
| SCHEMBL15523755 | 0.75 | KIT (0.48) | PTK2FLT4 | |
| SCHEMBL12478570 | 0.71 | RXFP1 (0.41) | PTK2FLT4 | |
| SCHEMBL15524296 | 0.69 | FFAR1 (0.36) | FLT4 | |
| SCHEMBL15524605 | 0.68 | FFAR1 (0.48) | — | |
| SCHEMBL15569325 | 0.68 | PTK2 (0.44) | PTK2FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015123722-A1 | INHIBITORS | BIONOMICS LIMITED (AU) | 2015-08-27 | — | — | WO | disclosed |
| WO-2015123722-A1 | INHIBITORS | BIONOMICS LIMITED (AU) | 2015-08-27 | — | — | WO | disclosed |