Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 20/20 | 0.54 |
| ▸ | FLT4 | P35916 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15569325 | 0.90 | PTK2 (0.44) | PTK2FLT4 | |
| SCHEMBL12478743 | 0.87 | PTK2 (0.44) | PTK2FLT4 | |
| SCHEMBL17040083 | 0.83 | PTK2 (0.56) | PTK2FLT4 | |
| SCHEMBL14617543 | 0.79 | ULK1 (0.43) | PTK2 | |
| SCHEMBL17027317 | 0.78 | PTK2 (0.36) | PTK2FLT4 | |
| SCHEMBL20459299 | 0.77 | PTK2 (0.74) | PTK2 | |
| SCHEMBL15524196 | 0.74 | PTK2 (0.74) | PTK2 | |
| SCHEMBL15588322 | 0.74 | FLT4 (0.73) | PTK2FLT4 | |
| SCHEMBL15524679 | 0.74 | FLT4 (0.73) | PTK2FLT4 | |
| SCHEMBL15524004 | 0.74 | PTK2 (0.67) | PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015123722-A1 | INHIBITORS | BIONOMICS LIMITED (AU) | 2015-08-27 | — | — | WO | disclosed |
| WO-2015123722-A1 | INHIBITORS | BIONOMICS LIMITED (AU) | 2015-08-27 | — | — | WO | disclosed |