SCHEMBL17027355

SCHEMBL17027355

O=C(O)C1C=C(Cl)C=CC1(O)Cl

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
TP53 P04637 1/20 0.31
ALOX15 P16050 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4942484 0.79 ALDH1A1 (0.31) ALDH1A1TP53ALOX15MAPK1SMN1; SMN2
SCHEMBL6129944 0.79 ALDH1A1 (0.31) ALDH1A1TP53ALOX15MAPK1SMN1; SMN2
SCHEMBL8148632 0.79 ALDH1A1 (0.31) ALDH1A1TP53ALOX15MAPK1SMN1; SMN2
SCHEMBL27761955 0.78
SCHEMBL330286 0.73
SCHEMBL28100453 0.72 ALDH1A1 (0.33) ALDH1A1TP53ALOX15MAPK1SMN1; SMN2
SCHEMBL10434620 0.71
SCHEMBL4188329 0.70
SCHEMBL8847080 0.70
SCHEMBL10945074 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114163325-B Method for synthesizing dicamba by using continuous flow reactor 江苏优嘉植物保护有限公司 2024-06-28 CN disclosed
CN-114163325-A Method for synthesizing dicamba by using continuous flow reactor 江苏优嘉植物保护有限公司 2022-03-11 CN disclosed
CN-209597165-U A kind of cutting kettle suitable for solid-liquid reaction SICHUAN FUSIDA BIO TECH DEV CO LTD 2019-11-08 CN disclosed
CN-106029618-B Process for producing 2, 5-dihalogenophenol ethers 巴斯夫欧洲公司 2019-01-18 CN disclosed
US-9957212-B2 Process for producing 2,5-dihalophenolethers BASF SE (DE) 2018-05-01 US disclosed
EP-3107884-B1 PROCESS FOR PRODUCING 2,5-DIHALOPHENOLETHERS BASF SE (DE) 2018-04-04 EP disclosed
CN-106831396-A A kind of improvement synthetic method of 5 chloro-salicylic acid 苏州市罗森助剂有限公司 2017-06-13 CN disclosed
US-20170008824-A1 PROCESS FOR PRODUCING 2,5-DIHALOPHENOLETHERS BASF SE (DE) 2017-01-12 US disclosed
EP-3107884-A1 PROCESS FOR PRODUCING 2,5-DIHALOPHENOLETHERS BASF SE (DE) 2016-12-28 EP disclosed
CN-106029618-A Process for producing 2, 5-dihalogenophenol ethers 巴斯夫欧洲公司 2016-10-12 CN disclosed
WO-2015124651-A1 PROCESS FOR PRODUCING 2,5-DIHALOPHENOLETHERS BASF SE (DE) 2015-08-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170008824-A1 PROCESS FOR PRODUCING 2,5-DIHALOPHENOLETHERS CYP4F2, CYP4F3, CYP4B1 ALDH1A1 116/4885TP53 2436/4885ALOX15 1706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.