SCHEMBL4942484

SCHEMBL4942484

O=C(O)C1C=C(Cl)C=CC1(Cl)C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
TP53 P04637 1/20 0.31
ALOX15 P16050 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17027355 0.79 ALDH1A1 (0.31) ALDH1A1TP53ALOX15MAPK1SMN1; SMN2
SCHEMBL6129944 0.78 ALDH1A1 (0.31) ALDH1A1TP53ALOX15MAPK1SMN1; SMN2
SCHEMBL28155255 0.78
SCHEMBL8148632 0.78 ALDH1A1 (0.31) ALDH1A1TP53ALOX15MAPK1SMN1; SMN2
SCHEMBL27761955 0.77
SCHEMBL4188329 0.73
SCHEMBL27501829 0.70 ALDH1A1 (0.31) ALDH1A1TP53ALOX15MAPK1SMN1; SMN2
SCHEMBL8847080 0.68
SCHEMBL330286 0.68
SCHEMBL6722075 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080003368-A1 PARTICULATE COATINGS HAVING IMPROVED CHIP RESISTANCE, UV DURABILITY, AND COLOR STABILITY BASF CORPORATION (US) 2008-01-03 US disclosed
EP-1629024-A1 PARTICULATE COATING HAVING IMPROVED CHIP RESISTANCE, UV DURABILITY, AND COLOR STABILITY BASF CORPORATION (US) 2006-03-01 EP disclosed
US-6881769-B1 Matting agents for thermally curable systems HUNTSMAN ADVANCED MATERIALS AMERICAS INC. (US) 2005-04-19 US disclosed
EP-1169395-B1 MATTING AGENTS FOR THERMALLY CURABLE SYSTEMS HUNTSMAN ADV MAT SWITZERLAND (CH) 2004-12-29 EP disclosed
WO-2004104066-A1 PARTICULATE COATING HAVING IMPROVED CHIP RESISTANCE, UV DURABILITY, AND COLOR STABILITY BASF CORPORATION (US) 2004-12-02 WO disclosed
US-20040236037-A1 Particulate coatings having improved chip resistance, UV durability, and color stability BASF CORPORATION 2004-11-25 US disclosed
EP-0881262-B1 Curable composition on the basis of polymers containing free carboxylic groups VANTICO AG (CH) 2003-11-19 EP disclosed
EP-1141153-B1 CROSSLINKING COMPOSITION FOR CARBOXYL-CONTAINING POLYMERS IN HEAT-CURABLE SYSTEMS VANTICO AG (CH) 2003-09-10 EP disclosed
EP-1169395-A1 MATTING AGENTS FOR THERMALLY CURABLE SYSTEMS Vantico AG (CH) 2002-01-09 EP disclosed
EP-0697440-B1 Heat-hardenable composition, especially suited for use as automotive paints VANTICO AG (CH) 2001-11-14 EP disclosed
EP-0980399-A1 MODIFIED EPOXY RESIN AND ITS USE AS A FORMULATING COMPONENT FOR HEAT-CURABLE COMPOSITIONS, ESPECIALLY FOR POWDER COATINGS Ciba SC Holding AG (CH) 2000-02-23 EP disclosed
EP-0881262-A2 Curable composition on the basis of polymers containing free carboxylic groups Ciba SC Holding AG (CH) 1998-12-02 EP disclosed
WO-1998050447-A1 MODIFIED EPOXY RESIN AND ITS USE AS A FORMULATING COMPONENT FOR HEAT-CURABLE COMPOSITIONS, ESPECIALLY FOR POWDER COATINGS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-11-12 WO disclosed
EP-0536085-B1 Solid compositions based on polyglycidyl compounds having a molecular weight lower than 1500 CIBA GEIGY AG (CH) 1998-11-11 EP disclosed
EP-0697440-A2 Heat-hardenable composition, especially suited for use as automotive paints CIBA-GEIGY AG (CH) 1996-02-21 EP disclosed
US-5457168-A Solid compositions of polyglycidyl compounds having a molecular weight of less than 1500 CIBA-GEIGY CORPORATION (US) 1995-10-10 US disclosed
US-5294683-A Curing agent for polyester CIBA-GEIGY CORPORATION (US) 1994-03-15 US disclosed
EP-0536085-A2 Solid compositions based on polyglycidyl compounds having a molecular weight lower than 1500 CIBA-GEIGY AG (CH) 1993-04-07 EP disclosed
US-4101528-A FLAME RETARDANT AVTEX FIBERS INC. (US) 1978-07-18 US disclosed
US-4059546-A Textile fiber blend comprising cellulosic fibers and ethylene 2,6-naphthalene dicarboxylate-halogenated comonomers copolyester fibers AVTEX FIBERS INC. (US) 1977-11-22 US disclosed