Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17022755 | 0.80 | APEX1 (0.31) | APEX1 | |
| SCHEMBL29252281 | 0.76 | DAO (0.39) | APEX1HTTDAOGRM5GRM2 | |
| Acetic Acid SCHEMBL29067578 | 0.71 | APEX1 (0.41) | APEX1 | |
| SCHEMBL6935087 | 0.70 | ALDH1A1 (0.35) | APEX1HTT | |
| SCHEMBL28624930 | 0.70 | APEX1 (0.39) | APEX1 | |
| SCHEMBL302029 | 0.70 | APEX1 (0.31) | APEX1 | |
| SCHEMBL29283322 | 0.69 | POLB (0.32) | DAO | |
| SCHEMBL17022749 | 0.67 | ALDH1A1 (0.31) | — | |
| SCHEMBL11346867 | 0.66 | APEX1 (0.34) | APEX1 | |
| SCHEMBL27572663 | 0.66 | TSHR (0.33) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015124797-A1 | DENTAL MATERIALS ON THE BASIS OF LOW-ODOR THIOLS | IVOCLAR VIVADENT AG (LI) | 2015-08-27 | — | — | WO | disclosed |