Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.45 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18113458 | 0.79 | KCNN4 (0.46) | KCNN4KCNE1KCNQ1HIF1AKIF11 | |
| SCHEMBL1478852 | 0.78 | CYP1A2 (0.51) | CYP1A2MEN1KMT2ASMN1; SMN2HIF1A | |
| SCHEMBL935388 | 0.74 | KCNN4 (0.51) | KCNN4KCNE1KCNQ1CYP1A2KMT2A | |
| SCHEMBL15535815 | 0.74 | KCNN4 (0.51) | KCNN4KCNE1KCNQ1CYP1A2KMT2A | |
| SCHEMBL714233 | 0.74 | KCNN4 (0.51) | KCNN4KCNE1KCNQ1CYP1A2KMT2A | |
| SCHEMBL1843171 | 0.74 | EPHX2 (0.40) | CYP1A2SMN1; SMN2CYP2C19GAAALDH1A1 | |
| SCHEMBL27335767 | 0.73 | KCNN4 (0.40) | KCNN4KCNE1KCNQ1HIF1ACYP2C19 | |
| SCHEMBL27448763 | 0.73 | KCNN4 (0.44) | KCNN4KCNE1KCNQ1KMT2AHIF1A | |
| SCHEMBL27901491 | 0.73 | KCNN4 (0.44) | KCNN4KCNE1KCNQ1CYP1A2MEN1 | |
| SCHEMBL11112539 | 0.73 | KCNN4 (0.41) | KCNN4KCNE1KCNQ1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231701-B1 | PEPTIDOMIMETICS WITH GLUCAGON ANTAGONISTIC AND GLP-1 AGONISTIC ACTIVITIES | CADILA HEALTHCARE LTD (IN) | 2012-04-18 | — | — | EP | disclosed |