Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702810 | 0.73 | KCNN4 (0.45) | KCNN4KCNE1KCNQ1KIF11CYP2C19 | |
| SCHEMBL935388 | 0.66 | KCNN4 (0.51) | KCNN4KCNE1KCNQ1KIF11CYP2C19 | |
| SCHEMBL15535815 | 0.66 | KCNN4 (0.51) | KCNN4KCNE1KCNQ1KIF11CYP2C19 | |
| SCHEMBL714233 | 0.66 | KCNN4 (0.51) | KCNN4KCNE1KCNQ1KIF11CYP2C19 | |
| SCHEMBL11112545 | 0.66 | ALDH1A1 (0.37) | SMN1; SMN2HIF1AALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27841045 | 0.64 | KCNN4 (0.57) | KCNN4KCNE1KCNQ1KIF11SMN1; SMN2 | |
| SCHEMBL17420795 | 0.63 | KCNN4 (0.52) | KCNN4KCNE1KCNQ1SMN1; SMN2CTNNB1 | |
| SCHEMBL31414989 | 0.63 | KCNN4 (0.52) | KCNN4KCNE1KCNQ1SMN1; SMN2CTNNB1 | |
| SCHEMBL3818506 | 0.63 | KCNN4 (0.52) | KCNN4KCNE1KCNQ1KIF11SMN1; SMN2 | |
| SCHEMBL21632343 | 0.63 | KCNN4 (0.47) | KCNN4KCNE1KCNQ1KIF11CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450159-A | ORGAN TRANSPLANTS; IMMUNOLOGY | THE UPJOHN COMPANY (US) | 1984-05-22 | — | — | US | disclosed |
| US-4352929-A | ANTIBODY INHIBITORS | THE UPJOHN COMPANY (US) | 1982-10-05 | — | — | US | disclosed |