Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.44 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27901479 | 0.80 | PTGDR2 (0.39) | RIPK1 | |
| SCHEMBL935388 | 0.76 | KCNN4 (0.51) | KCNN4KCNE1KCNQ1HIF1ACYP2C19 | |
| SCHEMBL714233 | 0.76 | KCNN4 (0.51) | KCNN4KCNE1KCNQ1HIF1ACYP2C19 | |
| SCHEMBL15535815 | 0.76 | KCNN4 (0.51) | KCNN4KCNE1KCNQ1HIF1ACYP2C19 | |
| SCHEMBL27869010 | 0.76 | ALDH1A1 (0.53) | HIF1ACYP2C19MEN1CYP1A2KMT2A | |
| SCHEMBL27467077 | 0.75 | KCNN4 (0.46) | KCNN4KCNE1KCNQ1RIPK1HIF1A | |
| SCHEMBL12273629 | 0.74 | KCNN4 (0.36) | KCNN4KCNE1KCNQ1RIPK1KIF11 | |
| SCHEMBL11826461 | 0.73 | KCNN4 (0.45) | KCNN4KCNE1KCNQ1RIPK1KIF11 | |
| SCHEMBL1702810 | 0.73 | KCNN4 (0.45) | KCNN4KCNE1KCNQ1RIPK1HIF1A | |
| SCHEMBL21632343 | 0.72 | KCNN4 (0.47) | KCNN4KCNE1KCNQ1RIPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068806-A | 1,4,5,6-tetrahydro-pyrimidin-2-ylamine compounds | SIENA BIOTECH SPA | 2013-04-24 | — | — | CN | disclosed |