⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615065 | 0.79 | PAOX (0.31) | — | |
| SCHEMBL27968687 | 0.77 | — | — | |
| SCHEMBL11599646 | 0.77 | — | — | |
| SCHEMBL1803265 | 0.77 | — | — | |
| SCHEMBL11797532 | 0.75 | CRBN (0.31) | — | |
| SCHEMBL9290938 | 0.75 | — | — | |
| SCHEMBL30388628 | 0.73 | TSHR (0.31) | — | |
| SCHEMBL4636977 | 0.73 | CYP1A2 (0.32) | — | |
| SCHEMBL4556800 | 0.71 | NPC1 (0.47) | — | |
| SCHEMBL4556797 | 0.71 | RIPK1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190142817-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | THE TEXAS A&M UNIVERSITY SYSTEM | 2019-05-16 | — | — | US | claimed |
| EP-3107537-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | The Texas A&M University System (US) | 2016-12-28 | — | — | EP | claimed |
| US-20160354358-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | THE TEXAS A&M UNIVERSITY SYSTEM | 2016-12-08 | — | — | US | claimed |
| WO-2015127089-A1 | COMPOSITIONS FOR DRUG SENSITIZATION OF PARASITES | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2015-08-27 | — | — | WO | claimed |
| US-11083717-B2 | Compositions and methods for drug sensitization of parasites | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2021-08-10 | — | — | US | disclosed |
| EP-3659597-A2 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | The Texas A&M University System (US) | 2020-06-03 | — | — | EP | disclosed |
| US-20200138796-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | THE TEXAS A&M UNIVERSITY SYSTEM | 2020-05-07 | — | — | US | disclosed |
| US-10543200-B2 | Compositions and methods for drug sensitization of parasites | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2020-01-28 | — | — | US | disclosed |
| US-20190142817-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | THE TEXAS A&M UNIVERSITY SYSTEM | 2019-05-16 | — | — | US | disclosed |
| US-10226455-B2 | Compositions and methods for drug sensitization of parasites | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2019-03-12 | — | — | US | disclosed |
| CN-108883090-A | Drug-sensitized composition and method for parasitic animal and plant | 得克萨斯州A&M大学系统 | 2018-11-23 | — | — | CN | disclosed |
| US-20180243275-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | THE TEXAS A&M UNIVERSITY SYSTEM | 2018-08-30 | — | — | US | disclosed |
| EP-3340979-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | The Texas A&M University System (US) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017035438-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-03-02 | — | — | WO | disclosed |
| EP-3107537-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | The Texas A&M University System (US) | 2016-12-28 | — | — | EP | disclosed |
| US-20160354358-A1 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | THE TEXAS A&M UNIVERSITY SYSTEM | 2016-12-08 | — | — | US | disclosed |
| WO-2015127089-A1 | COMPOSITIONS FOR DRUG SENSITIZATION OF PARASITES | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2015-08-27 | — | — | WO | disclosed |