Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16965772 | 0.83 | AOC3 (0.46) | NPC1RAB9AMEN1KMT2AAOC3 | |
| SCHEMBL6987578 | 0.82 | RORC (0.41) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL11221924 | 0.79 | NPC1 (0.46) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL4556797 | 0.76 | RIPK1 (0.42) | NPC1RAB9ALMNARIPK1 | |
| SCHEMBL19583957 | 0.74 | SMN1; SMN2 (0.42) | LMNA | |
| SCHEMBL22649387 | 0.73 | HDAC3 (0.43) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL9098649 | 0.73 | AKT1 (0.71) | NPC1RAB9ACA12AKT1 | |
| SCHEMBL967320 | 0.73 | LMNA (0.70) | NPC1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL3641494 | 0.72 | NPC1 (0.55) | NPC1RAB9ALMNAMEN1KMT2A | |
| SCHEMBL967112 | 0.72 | NPC1 (0.66) | NPC1RAB9AMEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009145360-A1 | BENZENE OR THIOPHENE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-12-03 | — | — | WO | claimed |