SCHEMBL1702848

SCHEMBL1702848

CCCCc1ccc(N(c2ccc(N)cc2)c2ccc(Br)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 2/20 0.46
▸ TAAR1 Q96RJ0 2/20 0.46
▸ MAPK1 P28482 3/20 0.45
▸ L3MBTL1 Q9Y468 3/20 0.45
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ NPC1 O15118 1/20 0.45
▸ NFKB1 P19838 1/20 0.45
▸ RAB9A P51151 1/20 0.45
▸ NFKB2 Q00653 1/20 0.45
▸ RELA Q04206 1/20 0.45
▸ MAPT P10636 2/20 0.45
▸ SKP2 Q13309 1/20 0.45
▸ ALDH1A1 P00352 3/20 0.43
▸ ALOX15 P16050 1/20 0.43
▸ CA2 P00918 2/20 0.43
▸ CA1 P00915 1/20 0.43
▸ MAOB P27338 2/20 0.43
▸ GFER P55789 2/20 0.42
▸ CYP3A4 P08684 2/20 0.41
▸ TDP1 Q9NUW8 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL753213 0.91 SMN1; SMN2 (0.51) HTR2ATAAR1MAPK1L3MBTL1SMN1; SMN2
SCHEMBL12313746 0.91 SMN1; SMN2 (0.51) HTR2ATAAR1MAPK1L3MBTL1SMN1; SMN2
SCHEMBL13475015 0.91 SMN1; SMN2 (0.51) HTR2ATAAR1MAPK1L3MBTL1SMN1; SMN2
SCHEMBL1046903 0.91 SMN1; SMN2 (0.51) HTR2ATAAR1MAPK1L3MBTL1SMN1; SMN2
SCHEMBL12313750 0.91 SMN1; SMN2 (0.51) HTR2ATAAR1MAPK1L3MBTL1SMN1; SMN2
SCHEMBL23086272 0.91 HTR2A (0.52) HTR2AMAPK1L3MBTL1SMN1; SMN2RAB9A
SCHEMBL992778 0.91 SMN1; SMN2 (0.51) HTR2ATAAR1MAPK1L3MBTL1SMN1; SMN2
SCHEMBL10358431 0.91 SMN1; SMN2 (0.51) HTR2ATAAR1MAPK1L3MBTL1SMN1; SMN2
SCHEMBL8671388 0.86 RARB (0.49) HTR2AL3MBTL1SMN1; SMN2NPC1RAB9A
SCHEMBL12439871 0.86 NPC1 (0.55) TAAR1MAPK1L3MBTL1SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1569980-B1 9-ARYL AND BISARYL SUBSTITUTED POLYFLUORENES CAMBRIDGE DISPLAY TECH LTD (GB) 2012-04-18 — — EP disclosed
EP-2363423-A1 9-aryl and bisaryl subtituted polyfluorenes CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2011-09-07 — — EP disclosed
US-7208567-B2 Polymer compound and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-24 — — US disclosed
EP-1569980-A2 9-ARYL AND BISARYL SUBSTITUTED POLYFLUORENES Cambridge Display Technology Limited (GB) 2005-09-07 — — EP disclosed
WO-2004041902-A2 9-ARYL AND BISAYL SUBSTITUTED POLYFLUORENES CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2004-05-21 — — WO disclosed
US-20040002576-A1 Polymer compound and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED 2004-01-01 — — US disclosed
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