Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.45 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5081467 | 0.93 | PBRM1 (0.59) | PBRM1SLC22A6KDM4EMAPTAPAF1 | |
| Acetic Acid SCHEMBL1716467 | 0.93 | PBRM1 (0.59) | PBRM1SLC22A6KDM4EMAPTAPAF1 | |
| Sulfuric Acid SCHEMBL27181503 | 0.91 | SLC22A6 (0.56) | PBRM1SLC22A6KDM4EMAPTMEN1 | |
| Sulfuric Acid SCHEMBL38066 | 0.91 | SLC22A6 (0.56) | PBRM1SLC22A6KDM4EMAPTMEN1 | |
| Sulfuric Acid SCHEMBL432422 | 0.90 | SLC22A6 (0.54) | PBRM1SLC22A6KDM4EMAPTMEN1 | |
| Pyruvate SCHEMBL29152649 | 0.86 | PBRM1 (0.56) | PBRM1SLC22A6KDM4EMAPTAPAF1 | |
| Sulfuric Acid SCHEMBL2114471 | 0.83 | SLC22A6 (0.51) | PBRM1SLC22A6KDM4EMAPTMEN1 | |
| Acetic Acid SCHEMBL27807549 | 0.83 | PBRM1 (0.56) | PBRM1SLC22A6KDM4EMAPTAPAF1 | |
| SCHEMBL155191 | 0.82 | MEN1 (0.58) | PBRM1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL29567690 | 0.82 | MEN1 (0.58) | PBRM1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110532-B1 | SYSTEMS FOR UTILIZING THE WATER CONTENT IN FLUID FROM A RENAL REPLACEMENT THERAPY PROCESS | AQUAPORIN AS (DK) | 2024-01-10 | — | — | EP | disclosed |
| CN-106573094-B | System for utilizing moisture in fluid from renal replacement therapy procedures | 博通分离膜技术（北京）有限公司 | 2020-06-05 | — | — | CN | disclosed |
| US-10293094-B2 | Systems for utilizing the water content in fluid from a renal replacement therapy process | AQUAPORIN A/S (DK) | 2019-05-21 | — | — | US | disclosed |
| US-20170065762-A1 | SYSTEMS FOR UTILIZING THE WATER CONTENT IN FLUID FROM A RENAL REPLACEMENT THERAPY PROCESS | AQUAPORIN A/S (DK) | 2017-03-09 | — | — | US | disclosed |
| EP-3110532-A1 | SYSTEMS FOR UTILIZING THE WATER CONTENT IN FLUID FROM A RENAL REPLACEMENT THERAPY PROCESS | Aquaporin A/S (DK) | 2017-01-04 | — | — | EP | disclosed |
| WO-2015124716-A1 | SYSTEMS FOR UTILIZING THE WATER CONTENT IN FLUID FROM A RENAL REPLACEMENT THERAPY PROCESS | AQUAPORIN A/S (DK) | 2015-08-27 | — | — | WO | disclosed |