Acetic Acid

Acetic Acid

SCHEMBL5081467

CC(=O)O.CC(=O)O.Oc1c[nH]c2ccccc12

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.59
SLC22A6 Q4U2R8 1/20 0.54
GPR84 Q9NQS5 1/20 0.53
KDM4E B2RXH2 3/20 0.53
MAPT P10636 3/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
ALDH1A1 P00352 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
HPGD P15428 1/20 0.53
APAF1 O14727 1/20 0.53
POLB P06746 1/20 0.53
RECQL P46063 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
LMNA P02545 3/20 0.51
TSHR P16473 2/20 0.51
BLM P54132 2/20 0.51
CYP1A2 P05177 1/20 0.51
PKM P14618 1/20 0.51
CYP2C19 P33261 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL1716467 1.00 PBRM1 (0.59) PBRM1SLC22A6GPR84KDM4EMAPT
Sulfuric Acid SCHEMBL17028779 0.93 PBRM1 (0.53) PBRM1SLC22A6GPR84KDM4EMAPT
Pyruvate SCHEMBL29152649 0.93 PBRM1 (0.56) PBRM1SLC22A6GPR84KDM4EMAPT
Acetic Acid SCHEMBL27807549 0.89 PBRM1 (0.56) PBRM1SLC22A6GPR84KDM4EMAPT
SCHEMBL29567690 0.88 MEN1 (0.58) PBRM1GPR84KDM4EMAPTMEN1
SCHEMBL155191 0.88 MEN1 (0.58) PBRM1GPR84KDM4EMAPTMEN1
Hydrochloric Acid SCHEMBL28628671 0.86 MEN1 (0.56) PBRM1GPR84KDM4EMAPTMEN1
SCHEMBL28624457 0.86 MEN1 (0.56) PBRM1GPR84KDM4EMAPTMEN1
Methane SCHEMBL5065725 0.86 MEN1 (0.56) PBRM1GPR84KDM4EMAPTMEN1
SCHEMBL10550137 0.86 MEN1 (0.56) PBRM1GPR84KDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240084002-A1 METHODS AND COMPOSITIONS UTILIZING IDO1-DEPENDENT VASCULARIZING CELLS FOR THE TREATMENT OF PATHOLOGICAL CONDITIONS INVOLVING NEOVASCULARIZATION LANKENAU INSTITUTE FOR MEDICAL RESEARCH (US) 2024-03-14 US claimed
EP-4255423-A1 METHODS AND COMPOSITIONS UTILIZING IDO1-DEPENDENT VASCULARIZING CELLS FOR THE TREATMENT OF PATHOLOGICAL CONDITIONS INVOLVING NEOVASCULARIZATION Lankenau Institute for Medical Research (US) 2023-10-11 EP claimed
US-11752131-B2 Methods and pharmaceutical compositions for the treatment of obesity INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) 2023-09-12 US claimed
WO-2022125553-A1 METHODS AND COMPOSITIONS UTILIZING IDO1-DEPENDENT VASCULARIZING CELLS FOR THE TREATMENT OF PATHOLOGICAL CONDITIONS INVOLVING NEOVASCULARIZATION LANKENAU INSTITUTE FOR MEDICAL RESEARCH (US) 2022-06-16 WO claimed
EP-1613308-A4 NOVEL METHODS FOR THE TREATMENT OF CANCER LANKENAU INST MEDICAL RES (US) 2008-02-20 EP claimed
EP-1613308-A1 NOVEL METHODS FOR THE TREATMENT OF CANCER Lankenau Institute for Medical Research (US) 2006-01-11 EP claimed
WO-2004093871-A1 NOVEL METHODS FOR THE TREATMENT OF CANCER LANKENAU INSTITUTE FOR MEDICAL RESEARCH (US) 2004-11-04 WO claimed
EP-3906415-B1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR ENHANCING CD8+ T CELL-DEPENDENT IMMUNE RESPONSES IN SUBJECTS SUFFERING FROM CANCER INST NAT SANTE RECH MED (FR) 2026-04-15 EP disclosed
EP-4713371-A1 ANTI-CATHEPSIN-D ANTIBODIES Institut National de la Santé et de la Recherche Médicale (FR) 2026-03-25 EP disclosed
US-20260061031-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF DILATED CARDIOMYOPATHY INST NAT SANTE RECH MED (FR) 2026-03-05 US disclosed
EP-4689658-A1 METHOD FOR DISCRIMINATING MONO-IMMUNOTHERAPY FROM COMBINED IMMUNOTHERAPY IN CANCERS Institut National de la Santé et de la Recherche Médicale (FR) 2026-02-11 EP disclosed
US-20260035471-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR ENHANCING CD8+ T CELL-DEPENDENT IMMUNE RESPONSES IN SUBJECTS SUFFERING FROM CANCER INST NAT SANTE RECH MED (FR) 2026-02-05 US disclosed
WO-2025202213-A9 LIPID NANOPARTICLE LOADED WITH ANTITUMORAL AGENT AND FUNCTIONNALIZED TO TARGET IMMOSUPPRESSIVE CELLS Institut National de la Santé et de la Recherche Médicale (FR) 2025-12-26 WO disclosed
US-6512100-B1 Yield chromogenic products after reactions catalyzed by sialidase take place, diagnosis; neuraminic acid derivatives IBBEX, INC. 2003-01-28 US disclosed
EP-1218390-A2 CHROMOGENIC SUBSTRATES OF SIALIDASE OF BACTERIAL, VIRAL, PROTOZOA, AND VERTEBRATE ORIGIN AND METHODS OF MAKING AND USING THE SAME Ibbex, Inc. (US) 2002-07-03 EP disclosed
US-20020004219-A1 Trypsin substrate and diganostic device, and method of using same SIEMENS HEALTHCARE DIAGNOSTICS INC. 2002-01-10 US disclosed
EP-1157984-A2 Trypsin substrate and diagnostic device, and method of using same Bayer Corporation (US) 2001-11-28 EP disclosed
EP-1124836-A1 CHROMOGENIC SUBSTRATES OF SIALIDASE AND METHODS OF MAKING AND USING THE SAME Ibbex, Inc. (US) 2001-08-22 EP disclosed
WO-2001025246-A2 CHROMOGENIC SUBSTRATES OF SIALIDASE OF BACTERIAL, VIRAL, PROTOZOA, AND VERTEBRATE ORIGIN AND METHODS OF MAKING AND USING THE SAME IBBEX, INC. (US) 2001-04-12 WO disclosed
WO-2000024753-A1 CHROMOGENIC SUBSTRATES OF SIALIDASE AND METHODS OF MAKING AND USING THE SAME IBBEX, INC. (US) 2000-05-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260061031-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF DILATED CARDIOMYOPATHY CD274, PDCD1, ICOS PBRM1 990/4885SLC22A6 2499/4885GPR84 793/4885
US-20020004219-A1 Trypsin substrate and diganostic device, and method of using same PRSS3, CTRL, PRSS2 PBRM1 3265/4885SLC22A6 3444/4885GPR84 2255/4885
US-20240084002-A1 METHODS AND COMPOSITIONS UTILIZING IDO1-DEPENDENT VASCULARIZING CELLS FOR THE TREATMENT OF PATHOLOGICAL CONDITIONS INVOLVING NEOVASCULARIZATION IDO1, IDO2, TIE1 PBRM1 3718/4885SLC22A6 4454/4885GPR84 1810/4885
US-11752131-B2 Methods and pharmaceutical compositions for the treatment of obesity IDO1, IDO2, GPR119 PBRM1 4331/4885SLC22A6 2452/4885GPR84 1077/4885
US-20260035471-A1 METHODS AND PHARMACEUTICAL COMPOSITIONS FOR ENHANCING CD8+ T CELL-DEPENDENT IMMUNE RESPONSES IN SUBJECTS SUFFERING FROM CANCER CD274, PDCD1LG2, PDCD1 PBRM1 849/4885SLC22A6 4056/4885GPR84 399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.