SCHEMBL17028974

SCHEMBL17028974

Clc1ccc(Cc2n[c]ns2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
PTGDR2 Q9Y5Y4 2/20 0.36
MAPT P10636 2/20 0.36
PRNP P04156 1/20 0.36
IDO1 P14902 3/20 0.35
AGXT P21549 2/20 0.35
HSP90AB1 P08238 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
HSD17B10 Q99714 1/20 0.35
LMNA P02545 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
NPC1 O15118 1/20 0.34
MAPK1 P28482 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL794861 0.81 ALDH1A1 (0.43) ALDH1A1TSHRHSD17B10LMNAL3MBTL1
SCHEMBL345646 0.71 ADORA3 (0.48) ALDH1A1MAPTLMNANPC1CYP1A2
SCHEMBL2091553 0.70 ALDH1A1 (0.46) ALDH1A1PTGDR2MAPTIDO1AGXT
SCHEMBL1106684 0.67 IDO1 (0.58) ALDH1A1MAPTIDO1AGXTHSP90AB1
SCHEMBL17028848 0.67 ALDH1A1 (0.50) ALDH1A1PTGDR2IDO1AGXTHSP90AB1
SCHEMBL5464791 0.67 ALDH1A1 (0.46) ALDH1A1PTGDR2MAPTIDO1AGXT
SCHEMBL17028967 0.64 ALDH1A1 (0.50) ALDH1A1MAPTHPGDHSD17B10LMNA
SCHEMBL17028856 0.63 HSP90AB1 (0.42) ALDH1A1MAPTPRNPIDO1HSP90AB1
SCHEMBL3027076 0.63 ALDH1A1 (1.00) ALDH1A1HPGDLMNAL3MBTL1MAPK1
SCHEMBL11105432 0.63 HSP90AB1 (0.42) ALDH1A1MAPTIDO1HSP90AB1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015124606-A1 N-SUBSTITUTED IMINO HETEROCYCLIC COMPOUNDS FOR COMBATING INVERTEBRATE PESTS BASF SE (DE) 2015-08-27 WO disclosed