Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16707667 | 0.91 | FKBP1A (0.49) | FKBP1ALMNAHTTMAPTALDH1A1 | |
| SCHEMBL16707643 | 0.91 | FKBP1A (0.49) | FKBP1ALMNAHTTMAPTALDH1A1 | |
| SCHEMBL17029146 | 0.85 | FKBP1A (0.58) | FKBP1ALMNAHTTMAPTALDH1A1 | |
| SCHEMBL16707647 | 0.85 | FKBP1A (0.58) | FKBP1ALMNAMAPTALDH1A1KMT2A | |
| SCHEMBL16707648 | 0.85 | FKBP1A (0.47) | FKBP1ALMNAMAPTALDH1A1KMT2A | |
| SCHEMBL16707645 | 0.84 | FKBP1A (0.45) | FKBP1ALMNAHTTMAPTALDH1A1 | |
| SCHEMBL16707644 | 0.83 | FKBP1A (0.43) | FKBP1ALMNAHTTMAPTALDH1A1 | |
| SCHEMBL17029173 | 0.83 | LMNA (0.50) | FKBP1ALMNAHTTMAPTALDH1A1 | |
| SCHEMBL21599142 | 0.83 | FKBP1A (0.45) | FKBP1ALMNAHTTMAPTALDH1A1 | |
| SCHEMBL16707658 | 0.80 | LMNA (0.44) | FKBP1ALMNAHTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115113-B2 | Azepane derivatives and methods of treating hepatitis B infections | NOVIRA THERAPEUTICS, INC. (US) | 2015-08-25 | — | — | US | disclosed |