Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17029175 | 0.96 | LMNA (0.70) | HTTL3MBTL1LMNAMAPTNPSR1 | |
| SCHEMBL17029145 | 0.93 | LMNA (0.76) | HTTL3MBTL1LMNAMAPTNPSR1 | |
| SCHEMBL16707664 | 0.92 | MAPT (0.64) | HTTL3MBTL1LMNAMAPTNPSR1 | |
| SCHEMBL17029164 | 0.89 | LMNA (0.69) | HTTL3MBTL1LMNAMAPTNPSR1 | |
| SCHEMBL16707792 | 0.88 | LMNA (0.65) | HTTL3MBTL1LMNAMAPTNPSR1 | |
| SCHEMBL17029189 | 0.88 | LMNA (0.65) | HTTL3MBTL1LMNAMAPTNPSR1 | |
| SCHEMBL17029152 | 0.86 | L3MBTL1 (0.63) | HTTL3MBTL1LMNAMAPTNPSR1 | |
| SCHEMBL17029162 | 0.86 | LMNA (0.63) | HTTL3MBTL1LMNAMAPTNPSR1 | |
| SCHEMBL17029165 | 0.85 | LMNA (0.70) | HTTL3MBTL1LMNAMAPTNPSR1 | |
| SCHEMBL17029148 | 0.85 | L3MBTL1 (0.65) | HTTL3MBTL1LMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115113-B2 | Azepane derivatives and methods of treating hepatitis B infections | NOVIRA THERAPEUTICS, INC. (US) | 2015-08-25 | — | — | US | disclosed |