SCHEMBL17029334

SCHEMBL17029334

C/C=C\C(CCCC)=N/C=N

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17029327 0.88 TRPA1 (0.33)
SCHEMBL24376192 0.72
SCHEMBL22425339 0.70
SCHEMBL24786528 0.66
SCHEMBL3641592 0.64 ALDH1A1 (0.40) CES2CES1
SCHEMBL3641594 0.64 ALDH1A1 (0.40) CES2CES1
SCHEMBL22421020 0.64
SCHEMBL19854811 0.64 CES1 (0.33) CES2CES1
SCHEMBL9444614 0.63
SCHEMBL19406444 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115096-B2 Fused heterocyclic compounds as ion channel modulators GILEAD SCIENCES, INC. (US) 2015-08-25 US disclosed