Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15199090 | 0.78 | CYP2C9 (0.34) | — | |
| SCHEMBL14537868 | 0.78 | ALDH1A1 (0.36) | POLBKDM4EALDH1A1GAAHPGD | |
| SCHEMBL15199091 | 0.78 | CYP2C9 (0.34) | — | |
| SCHEMBL13451458 | 0.76 | — | — | |
| SCHEMBL16015291 | 0.70 | SMN1; SMN2 (0.41) | POLBKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28573519 | 0.69 | KDM4E (0.42) | POLBKDM4EALDH1A1GAAHPGD | |
| SCHEMBL15014640 | 0.68 | KDM4E (0.41) | POLBKDM4EALDH1A1GAAHPGD | |
| SCHEMBL21743224 | 0.68 | KDM4E (0.41) | POLBKDM4EALDH1A1GAAHPGD | |
| SCHEMBL178337 | 0.68 | KDM4E (0.41) | POLBKDM4EALDH1A1GAAHPGD | |
| SCHEMBL1811883 | 0.67 | MAPT (0.37) | POLBKDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115127-B2 | Benzimidazole and azabenzimidazole compounds that inhibit anaplastic lymphoma kinase | AMGEN INC. (US) | 2015-08-25 | — | — | US | disclosed |