Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19186295 | 0.94 | CHRM2 (0.54) | GSRCHRM2CHRM4CHRM1GNAI3 | |
| SCHEMBL29622843 | 0.92 | LMNA (0.63) | GSRCHRM2CHRM4CHRM1GNAI3 | |
| SCHEMBL30421734 | 0.92 | GSR (0.52) | GSRCHRM2CHRM4CHRM1GNAI3 | |
| SCHEMBL29622881 | 0.92 | LMNA (0.63) | GSRCHRM2CHRM4CHRM1GNAI3 | |
| SCHEMBL3959872 | 0.92 | LMNA (0.63) | GSRCHRM2CHRM4CHRM1GNAI3 | |
| SCHEMBL9840679 | 0.91 | GSR (0.59) | GSRCHRM2CHRM4CHRM1GNAI3 | |
| SCHEMBL15131921 | 0.91 | PAOX (0.64) | GSRCHRM2CHRM4CHRM1GNAI3 | |
| SCHEMBL22188127 | 0.91 | GSR (0.50) | GSRCHRM2CHRM4CHRM1GNAI3 | |
| SCHEMBL32676289 | 0.91 | GNAI3 (0.64) | GSRCHRM2CHRM4CHRM1GNAI3 | |
| SCHEMBL3950764 | 0.91 | CHRM2 (0.51) | GSRCHRM2CHRM4CHRM1GNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2910573-A1 | ANTIBODY-DRUG CONJUGATE PRODUCED BY BINDING THROUGH LINKER HAVING HYDROPHILIC STRUCTURE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-08-26 | — | — | EP | disclosed |