Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 16/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 16/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905997 | 0.88 | SLC6A4 (0.52) | ICMTSLC6A4SLC6A3SLC6A2 | |
| SCHEMBL17029602 | 0.76 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL17029614 | 0.76 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5090502 | 0.75 | SLC6A4 (0.69) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL17452663 | 0.70 | SLC6A4 (0.56) | ICMTSLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3466072 | 0.67 | SLC6A4 (0.67) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7902544 | 0.66 | SLC6A4 (0.54) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5086827 | 0.66 | SLC6A4 (0.73) | SLC6A4SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL5302700 | 0.66 | SLC6A4 (0.70) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL9612074 | 0.66 | SLC6A4 (0.51) | SLC6A4SLC6A3SLC6A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393357-B1 | PYRROLIDINE TRIPLE REUPTAKE INHIBITORS | SUNOVION PHARMACEUTICALS INC (US) | 2015-08-26 | — | — | EP | disclosed |