Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 20/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 20/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20459079 | 0.88 | SLC6A4 (0.64) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL16691398 | 0.83 | SLC6A4 (0.70) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL17452663 | 0.81 | SLC6A4 (0.56) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7905997 | 0.78 | SLC6A4 (0.52) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL12614285 | 0.74 | SLC6A3 (0.45) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL17186853 | 0.74 | SLC6A4 (0.47) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL14986252 | 0.73 | SLC6A4 (0.50) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL14513169 | 0.73 | ALDH1A1 (0.50) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7532983 | 0.72 | ACHE (0.55) | SLC6A4 | |
| SCHEMBL31525724 | 0.71 | ALDH1A1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010091268-A1 | PYRROLIDINE TRIPLE REUPTAKE INHIBITORS | SEPRACOR INC. (US) | 2010-08-12 | — | — | WO | disclosed |