Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.45 |
| ▸ | ITGAV | P06756 | 8/20 | 0.45 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.45 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.45 |
| ▸ | MC4R | P32245 | 9/20 | 0.43 |
| ▸ | MC5R | P33032 | 9/20 | 0.43 |
| ▸ | MC3R | P41968 | 9/20 | 0.43 |
| ▸ | MC1R | Q01726 | 9/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2534766 | 0.94 | ITGB3 (0.48) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| SCHEMBL12547669 | 0.83 | ITGB3 (0.55) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| SCHEMBL21475019 | 0.83 | ITGB3 (0.55) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| SCHEMBL7743878 | 0.83 | ITGB3 (0.55) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| SCHEMBL19605481 | 0.83 | ITGB3 (0.55) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| SCHEMBL7743533 | 0.83 | ITGB3 (0.55) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| SCHEMBL14885799 | 0.83 | ITGB3 (0.55) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| SCHEMBL12808284 | 0.83 | ITGB3 (0.55) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| SCHEMBL16946584 | 0.83 | ITGB3 (0.55) | ITGB3ITGAVITGB5ITGB1ITGA5 | |
| SCHEMBL13107808 | 0.83 | ITGB3 (0.55) | ITGB3ITGAVITGB5ITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2182974-B1 | CYCLIC AZAPEPTIDES AS INTEGRIN MARKERS | SIEMENS MEDICAL SOLUTIONS (US) | 2015-08-26 | — | — | EP | disclosed |