SCHEMBL7743533

SCHEMBL7743533

N=C(N)NCCC[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(=O)O)NC(=O)CNC1=O

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 12/20 0.55
ITGAV P06756 8/20 0.55
ITGB5 P18084 5/20 0.55
ITGB1 P05556 2/20 0.55
ITGA5 P08648 2/20 0.55
ITGA2B P08514 4/20 0.54
MC4R P32245 8/20 0.54
MC5R P33032 8/20 0.54
MC3R P41968 8/20 0.54
MC1R Q01726 8/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14885799 1.00 ITGB3 (0.55) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL7743878 1.00 ITGB3 (0.55) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL16946584 1.00 ITGB3 (0.55) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL13107808 1.00 ITGB3 (0.55) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL16938095 1.00 ITGB3 (0.55) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL18968795 1.00 ITGB3 (0.55) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL12547669 1.00 ITGB3 (0.55) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL19581486 1.00 ITGB3 (0.55) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL21475019 1.00 ITGB3 (0.55) ITGB3ITGAVITGB5ITGB1ITGA5
SCHEMBL12808284 1.00 ITGB3 (0.55) ITGB3ITGAVITGB5ITGB1ITGA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4637836-A1 CYCLIC PEPTIDE-BASED LYSOSOME TARGETING DEGRADERS Wisconsin Alumni Research Foundation (US) 2025-10-29 EP claimed
US-20250197863-A1 GALNAC COMPOSITIONS FOR IMPROVING SIRNA BIOAVAILABILITY EMPIRICO INC (US) 2025-06-19 US claimed
EP-4493570-A2 GALNAC COMPOSITIONS FOR IMPROVING SIRNA BIOAVAILABILITY EMPIRICO INC. (US) 2025-01-22 EP claimed
WO-2024163404-A1 CYCLIC PEPTIDE-BASED LYSOSOME TARGETING DEGRADERS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2024-08-08 WO claimed
US-20240018523-A1 GALNAC COMPOSITIONS FOR IMPROVING SIRNA BIOAVAILABILITY EMPIRICO INC. 2024-01-18 US claimed
US-20230357774-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ANGIOPOIETIN LIKE 7 (ANGPTL7) RELATED DISEASES EMPIRICO INC. 2023-11-09 US claimed
WO-2023178144-A2 GALNAC COMPOSITIONS FOR IMPROVING SIRNA BIOAVAILABILITY EMPIRICO INC. (US) 2023-09-21 WO claimed
WO-2022140365-A1 GALNAC COMPOSITIONS FOR IMPROVING SIRNA BIOAVAILABILITY EMPIRICO INC. (US) 2022-06-30 WO claimed
WO-2022072356-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ANGIOPOIETIN LIKE 7 (ANGPTL7) RELATED DISEASES EMPIRICO INC. (US) 2022-04-07 WO claimed
EP-3976059-A2 TREATMENT OF ANGIOPOIETIN LIKE 7 (ANGPTL7) RELATED DISEASES EMPIRICO INC. (US) 2022-04-06 EP claimed
US-20260132230-A1 LIPID-POLYMER COMPOUNDS, COMPOSITIONS, AND USES THEREOF MIRUS BIO LLC (US) 2026-05-14 US disclosed
WO-2026090085-A1 TREATMENT OF CD33 RELATED DISEASES AND DISORDERS EMPIRICO INC. (US) 2026-04-30 WO disclosed
EP-4732849-A1 METHOD FOR IMPROVING STABILITY OF NUCLEIC ACID IN BLOOD AND IMPROVING TARGETING EFFICIENCY OF NUCLEIC ACID Kawasaki Institute of Industrial Promotion (JP) 2026-04-29 EP disclosed
EP-4731273-A2 HYDROGEL FORMULATIONS AND METHODS OF USE THEREOF Tempo Therapeutics, Inc. (US) 2026-04-29 EP disclosed
US-20260108638-A1 68GA- AND 64CU -NODAGA-E[C(RGDYK)]2 FOR USE AS PET TRACERS IN THE IMAGING OF ANGIOGENESIS IN HUMANS RIGSHOSPITALET (DK) 2026-04-23 US disclosed
US-20070134259-A1 Methods and compositions for pharmacologially controlled targeted immunotherapy THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2007-06-14 US disclosed
US-20070134259-A1 Methods and compositions for pharmacologially controlled targeted immunotherapy THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2007-06-14 US disclosed
US-20070116646-A1 Optical imaging of endometriosis KLAVENESS JO 2007-05-24 US disclosed
WO-2007056870-A1 METHODS AND COMPOSITIONS FOR PHARMACOLOGICALLY CONTROLLED TARGETED IMMUNOTHERAPY THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2007-05-24 WO disclosed
US-6537520-B1 Diagnosis and treatment of cancer; kit containing compound having peptide or peptidomimetic functionality that binds to a alpha v beta 3 receptor linked to a chelator BRISTOL-MYERS SQUIBB PHARMA COMPANY 2003-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108638-A1 68GA- AND 64CU -NODAGA-E[C(RGDYK)]2 FOR USE AS PET TRACERS IN THE IMAGING OF ANGIOGENESIS IN HUMANS VEGFA, FLT1, HIF1A ITGB3 324/4885ITGAV 597/4885ITGB5 1397/4885
US-20240018523-A1 GALNAC COMPOSITIONS FOR IMPROVING SIRNA BIOAVAILABILITY CSGALNACT1, B3GAT3, UGGT1 ITGB3 247/4885ITGAV 142/4885ITGB5 278/4885
US-20070134259-A1 Methods and compositions for pharmacologially controlled targeted immunotherapy HAVCR2, FCGR3B, CD47 ITGB3 505/4885ITGAV 355/4885ITGB5 554/4885
US-20250197863-A1 GALNAC COMPOSITIONS FOR IMPROVING SIRNA BIOAVAILABILITY CSGALNACT1, B3GAT3, UGGT1 ITGB3 247/4885ITGAV 142/4885ITGB5 278/4885
US-20260132230-A1 LIPID-POLYMER COMPOUNDS, COMPOSITIONS, AND USES THEREOF LIPE, PHOSPHO1, ATF4 ITGB3 4335/4885ITGAV 4152/4885ITGB5 4744/4885
US-20070116646-A1 Optical imaging of endometriosis LGALS3BP, SDF4, OGFRL1 ITGB3 599/4885ITGAV 743/4885ITGB5 224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.