SCHEMBL1702985

SCHEMBL1702985

Cc1ccc(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccccc4)c4ccc(C)cc4)cc3C)c(C)c2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
CYP2C19 P33261 2/20 0.42
MAPT P10636 2/20 0.42
KDM4E B2RXH2 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
APP P05067 1/20 0.37
TSHR P16473 2/20 0.37
LMNA P02545 1/20 0.37
ALOX12 P18054 1/20 0.37
ACHE P22303 1/20 0.37
CA12 O43570 1/20 0.37
CA9 Q16790 1/20 0.37
PTPRC P08575 1/20 0.36
MEN1 O00255 1/20 0.36
CRHBP P24387 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19408081 0.94 TDP1 (0.41) ALDH1A1L3MBTL1CYP2C19MAPTKDM4E
SCHEMBL1702523 0.94 ALDH1A1 (0.46) ALDH1A1L3MBTL1CYP2C19MAPTKDM4E
SCHEMBL1702280 0.92 ALDH1A1 (0.42) ALDH1A1L3MBTL1CYP2C19MAPTTDP1
SCHEMBL13990080 0.92 ESR2 (0.42) ALDH1A1L3MBTL1CYP2C19MAPTKDM4E
SCHEMBL14179890 0.91 ESR2 (0.41) ALDH1A1L3MBTL1CYP2C19MAPTKDM4E
SCHEMBL14944463 0.91 PTPRC (0.39) ALDH1A1L3MBTL1CYP2C19MAPTKDM4E
SCHEMBL13049550 0.89 ALDH1A1 (0.39) ALDH1A1L3MBTL1CYP2C19MAPTKDM4E
SCHEMBL13049541 0.89 ALDH1A1 (0.39) ALDH1A1L3MBTL1CYP2C19MAPTKDM4E
SCHEMBL1702731 0.89 ALDH1A1 (0.39) ALDH1A1L3MBTL1CYP2C19MAPTKDM4E
SCHEMBL17539995 0.89 ALDH1A1 (0.39) ALDH1A1L3MBTL1CYP2C19MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150037732-A1 METHOD FOR MANUFACTURING PHOTORECEPTOR LAYERS XEROX CORPORATION (US) 2015-02-05 US claimed
US-7267917-B2 Photoreceptor charge transport layer composition XEROX CORPORATION (US) 2007-09-11 US claimed
US-20060063080-A1 Photoreceptor charge transport layer composition XEROX CORPORATION (US) 2006-03-23 US claimed
US-6645686-B1 Electrophotographic imaging members XEROX CORPORATION 2003-11-11 US claimed
US-4299897-A Aromatic amino charge transport layer in electrophotography XEROX CORPORATION (US) 1981-11-10 US claimed
US-4047948-A Composite layered imaging member for electrophotography XEROX CORPORATION (US) 1977-09-13 US claimed
US-20150037732-A1 METHOD FOR MANUFACTURING PHOTORECEPTOR LAYERS XEROX CORPORATION (US) 2015-02-05 US disclosed
EP-1089130-B1 Process for fabricating an electrophotographic imaging member XEROX CORP (US) 2012-04-18 EP disclosed
US-7811728-B2 Imaging members and process for preparing same XEROX CORPORATION (US) 2010-10-12 US disclosed
US-7704656-B2 Photoconductive imaging member XEROX CORPORATION (US) 2010-04-27 US disclosed
US-7648811-B2 Branched polyarylene ethers and processes for the preparation thereof XEROX CORPORATION (US) 2010-01-19 US disclosed
US-7642028-B2 surface layers are a polymeric composition including a resin and a cyclic polymers such as polyethylene terephthalate, acrylic acid-ethylene copolymer, styrene-co-maleic anhydride copolymer; polyhexamethylene adipamide etc. and cyclic poly(bisphenol A carbonate), cyclic poly(bisphenol C carbonate) etc. XEROX CORPORATION (US) 2010-01-05 US disclosed
US-7491989-B2 Positive charging photoreceptor XEROX CORPORATION (US) 2009-02-17 US disclosed
US-4536458-A Migration imaging system XEROX CORPORATION (US) 1985-08-20 US disclosed
US-4515882-A CHARGE TRANSFER COMPOUNDS AND CHARGE INJECTION ENABLING PARTICLES XEROX CORPORATION (US) 1985-05-07 US disclosed
US-4299897-A Aromatic amino charge transport layer in electrophotography XEROX CORPORATION (US) 1981-11-10 US disclosed
US-4081274-A Composite layered photoreceptor XEROX CORPORATION (US) 1978-03-28 US disclosed
US-4078925-A Composite layered photoreceptor XEROX CORPORATION (US) 1978-03-14 US disclosed
US-4047948-A Composite layered imaging member for electrophotography XEROX CORPORATION (US) 1977-09-13 US disclosed
US-4047949-A Composite layered imaging member for electrophotography XEROX CORPORATION (US) 1977-09-13 US disclosed