SCHEMBL14944463

SCHEMBL14944463

Cc1ccc(N(c2ccc(C)cc2)c2ccc(-c3ccccc3C)c(C)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.39
ELANE P08246 1/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
GLA P06280 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 3/20 0.35
TSHR P16473 2/20 0.35
CYP2C19 P33261 3/20 0.35
CES1 P23141 1/20 0.35
RPS6KA2 Q15349 1/20 0.35
DHFR P00374 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11910081 0.92 DHFR (0.38) NPC1RAB9ASMN1; SMN2LMNAALOX15
SCHEMBL15014326 0.92 DHFR (0.38) NPC1RAB9ASMN1; SMN2LMNAALOX15
SCHEMBL1702985 0.91 ALDH1A1 (0.42) PTPRCELANEL3MBTL1MEN1LMNA
SCHEMBL1702280 0.90 ALDH1A1 (0.42) PTPRCELANEL3MBTL1MEN1LMNA
SCHEMBL12914259 0.89 MCL1 (0.39) ALDH1A1TSHRCYP2C19DHFRCYP1A2
SCHEMBL25495983 0.87 ESR1 (0.36) PTPRC
SCHEMBL11330854 0.86 PTPRC (0.34) PTPRCELANESMN1; SMN2MEN1LMNA
SCHEMBL14899560 0.86 MCL1 (0.41) NPC1RAB9ASMN1; SMN2L3MBTL1MEN1
SCHEMBL14179890 0.86 ESR2 (0.41) NPC1RAB9ASMN1; SMN2L3MBTL1MEN1
SCHEMBL11966926 0.86 ALDH1A1 (0.38) L3MBTL1MEN1LMNATP53KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9760030-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-09-12 US disclosed
US-20160116853-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-04-28 US disclosed
EP-2738610-B1 Electrophotographic photosensitive member, method for producing electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KK (JP) 2016-02-03 EP disclosed
EP-2738613-B1 Electrophotographic photosensitive member, method for producing electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KK (JP) 2016-02-03 EP disclosed
EP-2317390-B1 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KK (JP) 2014-09-24 EP disclosed
EP-2757420-A1 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus Canon Kabushiki Kaisha (JP) 2014-07-23 EP disclosed
WO-2013081171-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD OF PRODUCING THE SAME, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2013-06-06 WO disclosed
EP-1734411-B1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PRODUCTION METHOD FOR ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC DEVICE CANON KK (JP) 2013-05-15 EP disclosed