SCHEMBL1703002

SCHEMBL1703002

C=CCC(CC=C)(CCCCCCCCCC)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.42
ZDHHC2 Q9UIJ5 1/20 0.42
TSHR P16473 6/20 0.40
FAAH O00519 1/20 0.40
CES2 O00748 1/20 0.39
GPR84 Q9NQS5 6/20 0.38
PPARG P37231 6/20 0.38
PPARD Q03181 6/20 0.38
PPARA Q07869 6/20 0.38
HDAC11 Q96DB2 5/20 0.38
ALDH1A1 P00352 2/20 0.38
TLR2 O60603 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
FABP4 P15090 2/20 0.38
PTPN1 P18031 2/20 0.38
SLC22A6 Q4U2R8 1/20 0.38
SLC22A8 Q8TCC7 1/20 0.38
MEN1 O00255 1/20 0.38
ESR1 P03372 1/20 0.38
ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16414305 1.00 ZDHHC20 (0.42) ZDHHC20ZDHHC2TSHRFAAHCES2
SCHEMBL2143415 1.00 ZDHHC20 (0.42) ZDHHC20ZDHHC2TSHRFAAHCES2
SCHEMBL28966830 0.96 ZDHHC20 (0.42) ZDHHC20ZDHHC2TSHRFAAHCES2
SCHEMBL2143058 0.92 TSHR (0.39) ZDHHC20ZDHHC2TSHRFAAHGPR84
SCHEMBL28236149 0.90 ZDHHC20 (0.41) ZDHHC20ZDHHC2TSHRGPR84PPARG
SCHEMBL29111577 0.89 ZDHHC20 (0.40) ZDHHC20ZDHHC2TSHRGPR84PPARG
SCHEMBL1082264 0.89 PPARG (0.53) TSHRFAAHGPR84PPARGPPARD
SCHEMBL1286424 0.89 TERT (0.49) FAAHPPARGPPARDPPARATDP1
SCHEMBL28289760 0.89 ZDHHC20 (0.40) ZDHHC20ZDHHC2TSHRGPR84PPARG
SCHEMBL28191154 0.89 ZDHHC20 (0.40) ZDHHC20ZDHHC2TSHRGPR84PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440640-A1 A FLUID HAVING IMPROVED VISCOSITY INDEX Evonik RohMax Additives GmbH (DE) 2012-04-18 EP disclosed
WO-2010142789-A1 A FLUID HAVING IMPROVED VISCOSITY INDEX EVONIK ROHMAX ADDITIVES GMBH (DE) 2010-12-16 WO disclosed