Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA4 | P22748 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728575 | 0.76 | GPR84 (0.43) | TSHRDAONAPRTCES2CES1 | |
| SCHEMBL11422590 | 0.70 | GPR84 (0.42) | TSHRGPR84TP53ALDH1A1TDP1 | |
| SCHEMBL9999676 | 0.69 | GPR84 (0.40) | GPR84PKM | |
| SCHEMBL1531926 | 0.69 | LMNA (0.46) | CES2CES1GPR84CYP2C9ALDH1A1 | |
| SCHEMBL17030329 | 0.69 | TSHR (0.78) | TSHRDAONAPRTSRD5A2CES2 | |
| SCHEMBL79984 | 0.69 | TSHR (0.78) | TSHRDAONAPRTSRD5A2CES2 | |
| SCHEMBL20412248 | 0.69 | TSHR (0.78) | TSHRDAONAPRTSRD5A2CES2 | |
| SCHEMBL15168711 | 0.69 | TSHR (0.78) | TSHRDAONAPRTSRD5A2CES2 | |
| SCHEMBL13211931 | 0.68 | TSHR (0.43) | TSHRDAONAPRTSRD5A2CES2 | |
| SCHEMBL22020017 | 0.68 | GPR84 (0.38) | CES2CES1GPR84CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2910618-A1 | Luminescent hybrid nanomaterials with aggregation induced emission | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-08-26 | — | — | EP | disclosed |