Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23836917 | 0.82 | LOXL2 (0.46) | LOXL2PIN1DAOKDM4EALDH1A1 | |
| SCHEMBL1465644 | 0.82 | CYP2A6 (0.50) | LOXL2KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL1102337 | 0.80 | LOXL2 (0.50) | LOXL2PIN1DAOKDM4EALDH1A1 | |
| SCHEMBL15096307 | 0.77 | LOXL2 (0.42) | LOXL2PIN1DAOKDM4EALDH1A1 | |
| SCHEMBL1466706 | 0.76 | CYP19A1 (0.48) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL21959783 | 0.75 | KDM4E (0.60) | LOXL2PIN1DAOKDM4EALDH1A1 | |
| SCHEMBL23506812 | 0.73 | PIN1 (0.46) | LOXL2PIN1DAOKDM4EALDH1A1 | |
| SCHEMBL11865173 | 0.72 | LOXL2 (0.68) | LOXL2PIN1DAOKDM4EALDH1A1 | |
| SCHEMBL23750684 | 0.70 | CFTR (0.41) | — | |
| SCHEMBL14845691 | 0.69 | TP53 (0.56) | PIN1KDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007756-B1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMA (US) | 2015-08-26 | — | — | EP | disclosed |