Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14589668 | 0.83 | MCHR1 (0.51) | MCHR1ALDH1A1TP53TDP1RECQL | |
| SCHEMBL1866694 | 0.76 | ALDH1A1 (0.46) | MCHR1ALDH1A1RECQLHTTGAA | |
| SCHEMBL4401126 | 0.75 | GAA (0.59) | ALDH1A1CYP3A4CYP2C9CYP2C19HTT | |
| SCHEMBL16346863 | 0.74 | ALDH1A1 (0.53) | ALDH1A1TP53TDP1RECQLCYP3A4 | |
| SCHEMBL4112137 | 0.73 | LMNA (0.52) | MCHR1ALDH1A1TP53TDP1RECQL | |
| SCHEMBL28646256 | 0.73 | CA12 (0.46) | MCHR1ALDH1A1TP53TDP1CYP3A4 | |
| SCHEMBL9083678 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TP53TDP1RECQLCYP3A4 | |
| SCHEMBL16346612 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TP53TDP1RECQLCYP3A4 | |
| SCHEMBL257997 | 0.71 | MAPT (0.64) | MCHR1ALDH1A1TP53TDP1RECQL | |
| SCHEMBL20462898 | 0.71 | CYP3A4 (0.58) | ALDH1A1CYP3A4CYP2C19HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9295983-B2 | Calixarene-bound iridium-containing metal colloids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-03-29 | — | — | US | disclosed |
| US-20150238949-A1 | CALIXARENE-BOUND IRIDIUM-CONTAINING METAL COLLOIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150238949-A1 | CALIXARENE-BOUND IRIDIUM-CONTAINING METAL COLLOIDS | CALR, CALD1, CALU | MCHR1 1241/4885ALDH1A1 1391/4885TP53 979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.