Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | CTNNB1 | P35222 | 12/20 | 0.67 |
| ▸ | WNT3A | P56704 | 8/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19399114 | 0.91 | CTNNB1 (0.64) | HPGDCTNNB1WNT3APKMTSHR | |
| SCHEMBL653025 | 0.85 | PKM (0.87) | HPGDCTNNB1WNT3APKMTSHR | |
| SCHEMBL20827392 | 0.83 | HPGD (1.00) | HPGDCTNNB1WNT3APKMTSHR | |
| SCHEMBL1535157 | 0.80 | ATM (0.72) | HPGDCTNNB1WNT3APKMTSHR | |
| SCHEMBL10027736 | 0.80 | CTNNB1 (1.00) | HPGDCTNNB1WNT3APKMTSHR | |
| SCHEMBL27611333 | 0.80 | HPGD (0.82) | HPGDCTNNB1WNT3APKMTSHR | |
| SCHEMBL22638726 | 0.80 | CTNNB1 (0.72) | HPGDCTNNB1WNT3APKMTSHR | |
| SCHEMBL22638740 | 0.80 | HPGD (0.71) | HPGDCTNNB1WNT3APKMTSHR | |
| SCHEMBL1443787 | 0.80 | PKM (1.00) | HPGDCTNNB1WNT3APKMTSHR | |
| SCHEMBL26728280 | 0.80 | ATM (0.71) | HPGDCTNNB1WNT3APKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MRPL21, Q6ZSR9, SPOUT1 | HPGD 1747/4885CTNNB1 4248/4885WNT3A 3980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.