SCHEMBL17033552

SCHEMBL17033552

c1ccc(-c2cccc(-n3c4ccccc4c4c3ccc3cc5c6ccccc6c6ccccc6n5c34)c2)nc1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.41
HTR7 P34969 1/20 0.41
DHFR P00374 1/20 0.38
MCL1 Q07820 3/20 0.35
GRM5 P41594 7/20 0.35
NPY5R Q15761 1/20 0.34
IRAK4 Q9NWZ3 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PTGER1 P34995 1/20 0.32
HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16066861 0.90 HTR1A (0.40) HTR1AHTR7DHFRMCL1GRM5
SCHEMBL17033597 0.87 HTR1A (0.43) HTR1AHTR7DHFRMCL1GRM5
SCHEMBL17033792 0.87 HTR1A (0.42) HTR1AHTR7DHFRGRM5KDM4E
SCHEMBL17033555 0.87 MCL1 (0.34) HTR1AHTR7DHFRMCL1GRM5
SCHEMBL17033558 0.86 ATM (0.41) HTR1AHTR7KDM4EATML3MBTL1
SCHEMBL17033562 0.85 KDM4E (0.35) KDM4EATML3MBTL1
SCHEMBL17033571 0.85 DHFR (0.34) DHFRGRM5KDM4EATML3MBTL1
SCHEMBL9955519 0.85 HTR1A (0.43) HTR1AHTR7DHFRMCL1GRM5
SCHEMBL17033553 0.84 KDM4E (0.35) KDM4EATML3MBTL1
SCHEMBL16066436 0.84 HTR1A (0.42) HTR1AHTR7DHFRMCL1GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015125986-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-08-27 WO disclosed