SCHEMBL17033732

SCHEMBL17033732

c1ccc2c(c1)ccc1cc(-n3c4ccccc4c4ccc5c(cc6c7ccccc7c7ccccc7n65)c43)ccc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.38
ALDH1A1 P00352 3/20 0.36
HSD17B10 Q99714 2/20 0.36
CYP1B1 Q16678 2/20 0.36
HIF1A Q16665 1/20 0.36
CYP1A2 P05177 3/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
CYP2A6 P11509 1/20 0.32
TSHR P16473 1/20 0.32
PDPK1 O15530 3/20 0.32
CYP1A1 P04798 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
ERBB2 P04626 1/20 0.31
FYN P06241 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17033776 0.93 PMM2 (0.37) HPRT1ALDH1A1KDM4EATML3MBTL1
SCHEMBL17033667 0.86 HPRT1 (0.38) HPRT1ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL17033863 0.85 HPRT1 (0.37) HPRT1ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL17033507 0.84 HPRT1 (0.38) HPRT1ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL17033761 0.83 KDM4E (0.46) ALDH1A1KDM4EATML3MBTL1MAPT
SCHEMBL20825820 0.82 KDM4E (0.42) HPRT1ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL22186224 0.82 ALDH1A1 (0.37) HPRT1ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL17228249 0.81 KDM4E (0.52) HPRT1ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL17033489 0.81 ALDH1A1 (0.35) HPRT1ALDH1A1HSD17B10CYP1B1HIF1A
SCHEMBL17033758 0.81 HSD17B1 (0.38) CYP1A2CYP2C9CYP2C19KDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015125986-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-08-27 WO disclosed