SCHEMBL17033845

SCHEMBL17033845

c1ccc(-c2ccc(-c3nc(-c4ccc(-c5ccccn5)cc4)nc(-n4c5ccccc5c5c4ccc4cc6c7ccccc7c7ccccc7n6c45)n3)cc2)nc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPY5R Q15761 1/20 0.35
DHODH Q02127 1/20 0.33
MCL1 Q07820 1/20 0.33
CHEK2 O96017 1/20 0.32
KDM4E B2RXH2 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
MAPT P10636 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
PPP1CA P62136 1/20 0.31
KMT2A Q03164 1/20 0.31
AURKA O14965 1/20 0.31
IRAK4 Q9NWZ3 1/20 0.30
SLC6A7 Q99884 1/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17033864 0.93 DHODH (0.36) NPY5RDHODHMCL1CHEK2AURKA
SCHEMBL17033555 0.92 MCL1 (0.34) NPY5RMCL1KDM4ETDP1IRAK4
SCHEMBL17033798 0.89 DHODH (0.35) NPY5RDHODHMCL1CHEK2KDM4E
SCHEMBL17033653 0.88 MCL1 (0.36) NPY5RDHODHMCL1CHEK2KDM4E
SCHEMBL17033844 0.87 MEN1 (0.31) NPY5RKDM4EMAPTKMT2AALDH1A1
SCHEMBL17033392 0.87 KDM4E (0.32) KDM4EMAPTKMT2AALDH1A1TSHR
SCHEMBL17033826 0.85 BMX (0.33) MAPTKMT2ATSHR
SCHEMBL17033514 0.83 NPY5R (0.39) NPY5RDHODHMCL1CHEK2KDM4E
SCHEMBL17033834 0.82 CYP1A1 (0.37) KDM4EMAPTCYP1A2KMT2AALDH1A1
SCHEMBL17033552 0.82 HTR1A (0.41) NPY5RMCL1KDM4EIRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015125986-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2015-08-27 WO disclosed